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34062 Atherothrombosis v21 Overview of Atherothrombotic Therapy: Secondary Prevention 2002 ACC/AHA UA/NSTEMI* Guideline Update: Risk Factor Modification Class I Smoking cessation Achieving optimal weight Daily exercise AHA diet BP control to 130/85 mm Hg Tight control of hyperglycemia in diabetes HMG-CoA reductase inhibitor for LDL-C 130 mg/dL Lipid-lowering agent if LDL-C after diet is 100 mg/dL A fibrate or niacin if HDL-C 40 mg/dL Risk Reduction in Nonfatal MI When Patients With CHD Stop Smoking The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure In persons older than 50 years, SBP of 140 mm Hg is a much more important CVD risk factor than diastolic DBP. The risk of CVD, beginning at 115/75 mm Hg, doubles with each increment of 20/10 mm Hg. Individuals with a SBP of 120 to 139 mm Hg or a DBP of 80 to 89 mm Hg should be considered prehypertensive and require health-promoting lifestyle modifications to prevent CVD. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure Thiazide-type diuretics should be used in drug treatment for most patients with uncomplicated hypertension, either alone or combined with drugs from other classes Most patients with hypertension will require 2 or more antihypertensive medications to achieve goal BP (140/90 mm Hg, or 130/80 mm Hg for patients with diabetes or chronic kidney disease) If BP is 20/10 mm Hg above goal BP, consideration should be given to initiating therapy with 2 agents, 1 of which usually should be a thiazide-type diuretic The most effective therapy prescribed by the most careful clinician will control hypertension only if patients are motivated Classification and Management of Adult Blood Pressure Algorithm for Treatment of Hypertension 2002 ACC/AHA UA/NSTEMI* Guidelines : Recommendations for Long-term Medical Therapy Class I Aspirin 75 to 325 mg/day Clopidogrel 75 mg dai