International Nucleotide Sequence Database …：国际核苷酸序列数据库….pptVIP

Nucleic Acid Sequences Dataflow Database Entry Structure Description / Source Submitter Reference / Citation Feature Table TREMBL entry Sequence Database Divisions Nucleotide base codes (IUPAC) Authority Nomenclature Committee of the  International Union of Biochemistry Symbol Meaning a a; adenine c c; cytosine g g; guanine t t; thymine in DNA; uracil in RNA m a or c r a or g w a or t s c or g y c or t k g or t v a or c or g; not t h a or c or t; not g d a or g or t; not c b c or g or t; not a n a or c or g or t Unified centralized sequence-based taxonomy goal: consistent nomenclature and classification amongst collaborators EMBL Database growth: Jun2000 6. 7 million entries / 8.2 Gbases Jun2001 12 million entries / 12.8 Gbases Mar2002 15.8 million entries / 17.8 Gbases Taxonomic growth: number of organisms increased by ~ 30% to over 75000 Database statistics http://www3.ebi.ac.uk/Services/DBStats/ Taxonomic lineage Identifiers and data integration Accession Numbers 1+5 format: X46455 2+6 format: AJ343321  Feature Table Feature Table Components Location Descriptors Operators Feature Keysbiological nature of annotated feature attenuator Sequence related to transcription termination CAAT_signal CAAT box in eukaryotic promoters CDS Protein Coding Sequence (includes stop) enhancer Cis-acting enhancer of promoter function exon Region that codes for part of spliced mRNA mat_peptide Mature peptide coding region (stop not included) misc_feature Region of biological significance that cannot be described by any other feature mRNA Messenger RNA sig_peptide Signal peptide coding region source Biological source of the sequence vari