不同地区肾结石患者血清和尿液微量元素水平icp-ms测定及比较-determination and comparison of trace element levels in serum and urine of kidney stone patients in different regions by icp - ms.docxVIP

5 5 aluminum, copper higher (P0.05); The content of calcium, aluminum, copper, fluoride, cadmium in kidney stone patients serum was higher than healthy people(P0.05), while magnesium, zinc lower (P0.05); The content of urine magnesium, lithium and selenium in kidney stone patients from Longyan area was higher than from Xiamen area(P0.05); The content of serum calcium and ferrum in kidney stone patients from Longyan area was higer than from Xiamen area (P0.05). Conclusions Due to significant difference on trace elements metabolism between kidney stone patients and healthy people, The ICP-MS can be used to detect the content of trace element by discriminant analysis.Longyan and Xiamen trace elements in in kidney stone patients with calcium oxalate stone had a significant difference, so as to provide the basis for the diagnosis and prevention in kidney stones patients from different regions. Keywords Kidney stones; Calcium oxalate; inductively coupled plasma mass spectrometry; trace elements; partial least square discriminant analysis 1 1 英文缩略词表 英文缩写 英文全称 中文全称 ICP-MS induetively coupled Plasma mass speetrometr 电感耦合等离子体质谱 CPR Computer Pattern recognition 计算机模式识别 CaOxa Calcium oxalate 草酸钙 PLS partial least squares 偏最小二乘法 LDA linear discrimination analysis 线性判别模型 LD logistic discrimination logistic 判别模型 RSD relative standard deviation 相对标准偏差 LOD variation coefficients 检出限 VC variation coefficients 变异系数 PLS-DA partial least square discriminant analysis 偏最小二乘判别分析 微量元素对照表 英文缩写 英文全称 中文名称 英文缩写 英文全称 中文名称 7Li lithium 锂 60Ni nickel 镍 63Cu 13AL Aluminum 铝 copper 铜 22Ti titanium 钛 66Zn zinc 锌 24Mg magnesium 镁 75As arsenic 砷 43Ca calcium 钙 81Tl thallium 铊 51V Vanadium 钒 82Se selenium 硒 53Cr chromium 铬 95Mo molybdenum 钼 55Mn manganese 锰 111Cd cadmium 镉 57Fe ferrum 铁 118Sn tin 锡 学位论文原创性声明和版权使用授权书 学位论文原创性声明 本人郑重声明：所呈交的学位论文，是本人在导师的指导下，独立进行研究 工作所取得的真实成果。除文中已注明引用的内容外，本论文不含任何其他个人 或集体已经发表或撰写过的作品成果。对本论文的研究做出重要贡献的个人和集 体，均已在文中以明确方式标明。本人完全意识到本声明的法律结果由本人承担。 作者签名（手写）： 导师签名（手写）：