博茨瓦纳眼球摘除术探讨-discussion on eyeball extirpation in botswana.docxVIP

TABLE OF CONTENTSABSTRACT5ABBREVIATIONS7BACKGROUND8Types of surgical eye removal8Enucleation9Evisceration9Exenteration9Indications for surgical eye removal10LITERATURE REVIEW11Enucleation and Evisceration12Exenteration13METHODOLOGY14Study Design14Justification for the choice of study design and setting14Limitations15Strengths16SAMPLE SELECTIONS18Target Population18Inclusion Criteria18Exclusion Criteria18STUDY PROCEDURES20STATISTICAL PLAN21Study population21Sample area21Sample size22Data Collection Method24Demographics24Description of Outcome Statements24Data Analysis and Presentation25DATA HANDLING AND RECORD KEEPING26Confidentiality and Privacy26Informed Consent26Records Retention27ETHICAL CONSIDERATIONS28Benefits29Risks29RESULTS31DISCUSSION36CONCLUSION/ RECOMMENDATIONS40DEDICATION 42REFERENCES 43ABSTRACTSetting: The study was conducted in the largest tertiary center in a resource poor setting.Objectives: To determine the prevalence and describe the indications of surgical eye removals at Princess Marina Referral Hospital (PMRH), the largest single provider of ophthalmic care in Botswana.Methods/Design A descriptive hospital based survey was conducted. Retrospective case series involving a review of surgical records of all surgical eye removal procedures done between January 2010 and January 2013 at Princess Marina Referral Hospital. Information collected included basic demographic data, diagnosis, visual acuity at diagnosis and the eye affected. The etiology responsible was determined from history, clinical examination and investigations as contained in the existing records. The primary clinical indications for eye removal were categorized into infections, trauma, neoplasms, and others. Data were summarized using summary statistics and simple percentages.Results: A total of 728 patient records were reviewed, among which seventy-three (73) underwent surgical eye removal (enucleation, evisceration, and exenteration). This accounted for 10.0 % (73) of total ophthalm