磁场对大鼠股骨干骨折愈合中vegf fgf和tgf-β的影响-effects of magnetic field on vegf fgf and tgf - β in the healing of femoral shaft fractures in rats.docxVIP

磁场对大鼠股骨干骨折愈合中V磁场对大鼠股骨干骨折愈合中VEGF、FGF和TGF-β的影响万方数据万方数据strong rotating magnetic field can obviously promote the intervention callus growth. Constant strong intervention can promote VEGF rotating magnetic field induced the formation of blood vessels ability increases, constant strong rotating magnetic field in two weeks and three weeks in significantly promote bFGF expression, in the four weeks of promoting the expression of aFGF, Constant strong rotating magnetic field in the two weeks after the fracture promote TGF-β1 expression, and may promote mesenchymal cells for the proliferation and differentiation of cartilage cells and the osteoblast and participate in the fracture of the relevant repair; And after 3 and 4 weeks of the fracture can significantly promote TGF-beta 2 expression, indicating that the magnetic field not only make intervention TGF-beta 2 continuous transformation of cartilage cells ability strengthens, may also has some relationship with the osteoblast activity .Key words: RCSMF； Fracture；Immunochemistry；Growth Factor论文随机验证编号：BT5781623857VII目录1 前言 ........................................................................................................42 文献综述 ................................................................................................52.1 磁场的生物学作用 ............................................52.1.1 磁场对于骨组织代谢的影响................................................................................ 52.1.2 磁场对于血液循环的影响................................................................................... 62.1.3 磁场对于铁代谢相关蛋白的影响....................................................................... 62.2 骨折动物模型的制备 ..........................................72.2.1 闭合性骨折模型 .................................................................................................. 72.2.2 开放性骨折模型 .................................................................................................. 82.3 骨折愈合过程中的免疫组织化学研究 ............................8 HYPERLINK \l _TOC_250