过渡金属pd cu催化下的水相中heck偶联反应的研究-study on heck coupling reaction in aqueous phase catalyzed by transition metal pd cu.docx

万方数据万方数据were mild without inert gas protection, the scope of the substrate is relatively wide.Ligand-free CuI/TBAB catalytic system with NaOH as a base has been devoleped for Heck reaction in water. Different substituted aryl iodides, aryl bromides reacted with n-butyl acrylate and styrene very smoothly and afforded the corresponding products with yields of 61-95%. The ligand-free copper as a catalyst is cheaper, and the catalyst can be reused. The reaction conditions are mild in water, and the scope of the substrate is relatively broad.Keywords: Heck coupling reaction, salicylaldehyde imine,