右美托咪定用于气管异物取出术麻效果评价.docVIP

右美托咪定用于气管异物取出术麻醉效果评价 　　【摘要】 目的：探讨右美托咪定用于小儿气管异物取出术麻醉效果。方法：选择本院急诊行气管异物取出术的患儿50例，随机分为对照组和试验组，每组25例，分别在全麻诱导前10 min内静脉输注氯化钠溶液或右美托咪定（0.5 ?g/kg）。术中用丙泊酚和瑞芬太尼诱导和维持麻醉。记录入手术室时（T0）、置支气管镜前1 min（T1）、置支气管镜时（T2）、置支气管镜后1 min（T3）、退支气管镜时（T4）的HR、BP和SpO2，术中丙泊酚和瑞芬太尼用量，术后呛咳、躁动、呕吐等的发生例数和苏醒时间等。结果：两组间各时间点HR、MAP、SpO2比较无差异（P0.05）。与对照组比较，试验组手术过程中丙泊酚和瑞芬太尼用量减少（P0.05）。结论：在气管异物取出术中，右美托咪定能减少丙泊酚和瑞芬太尼的用量，术后苏醒质量好。 中国论文网 /6/viewhtm 　　【关键词】 右美托咪定； 气管异物； 儿童 　　【Abstract】 Objective：To investigate the application of Dexmedetomidine to the pediatric tracheobronchial foreign body removal surgery，and observe the anesthetic effects.Method：Fifty children undergoing tracheobronchial foreign body removal surgery were randomly divided into two groups：control group and experimental group.Two groups receiving intravenous infusion of normal saline and Dexmedetomidine 0.5 ?g/kg respectively within 10 min before the induction of anesthesia.Propofol and Remifentanil were used during the induction and maintenance of anesthesia.HR，BP and SpO2 at the time of enter the operating room，1 min before，the moment and 1 min after bronchoscopy inserted，bronchoscopy extract were recorded.The dosage of propofol and remifentanil were counted.Incidence rate of postoperative bucking，restlessness and vomiting were recorded.Measured the recovery time.Result：There were no significant differences in HR，BP and SpO2 between the two groups at each time point（P0.05）.Compared with control group，the dosage of Propofol and Remifentanil in experimental group were smaller（P0.05）.Conclusion：In the surgery of removing foreign body in trachea，Dexmedetomidine can reduce the dosage of propofol and remifentanil， the quality of postoperative recovery is good. 　　【Key words】 Dexmedetomidine； Tracheobronchial foreign body； Children 　　First-author’s address：The First Affiliated Hospital of Guangxi Medical University，Nanning 530021，China 　　doi：10.3969/j.issn.1674-4985.2016.11.002 　　小儿气管异物是危及儿童生命的临床急症，3岁以下小儿为高发人群，治疗的唯一方式是手术取出异物[1]。小儿的呼吸循环代偿能力差，置入