探究清胆通郁汤治疗急性胆管炎的临床研究.pdfVIP

提 要 本文运用传统的中医思维方式，从理论、临床两方面对急性胆管炎的病因病机和 治则治法进行深入的探讨，以寻求治疗急性胆管炎的有效方药。本文提出急性胆管炎 肝胆郁滞、肝胆脾胃不和，兼夹瘀血、湿热毒的病机假说，拟定疏肝利胆退黄、活血 祛瘀止痛、利湿清热解毒、健脾扶正之法，据此遣药组方，治疗急性胆管炎患者 30 例，并与30例抗生素对照组作比较研究。两组均治疗10天，对症状、体征、舌象、 脉象等进行了综合评定。结果表明，清胆通郁汤治疗组临床治愈率为76.67％，总有 效率为 90.00％，明显优于对照组的单纯抗生素治疗，具有显著性差异（P0.05）。 两组比较，治疗前肝功能无显著性差异（P0.05），治疗后具有显著性差异（P0.05)。 结论：清胆通郁汤治疗急性胆管炎不仅具有显著的临床疗效，而且具有坚实的药理药 效学基础，证明该药是治疗急性胆管炎的有效复方。本文从理论上深化了中医学对急 性胆管炎的病机认识，对该病的治疗提出了新的研究思路和治疗方药，为丰富该病的 治疗学做出了有益的尝试。 关键词 清胆通郁汤；急性胆管炎；胆郁蕴热、瘀毒内滞；中医药治疗 The Clinical Study of Treating Acute Cholangitis with Qingdantongyu Decoction Speciality: Medicine of TCM Author: Gao Xiulan Tutor: Professor Cao Zhiqun Abstract To search after the effective medicine to Acute Cholangitis, the article, on the base of the traditional Chinese medicine, theoretically and clinically discusses the cause and the mechanism of the disease, and the treatment of the disease.The article advances a new mechanism of Acute Cholangitis that the disease is mainly caused by hepatocholic stasis, gastrosplenic and hepatocholic incoordination with blood stasis and toxin of dampness-heat. According to this mechanism, a new prescription of Qingdantongyu Decoction had been drawn up to treat 30 patients. A Clinical Observation had been carried out, and the treatment group (30 cases) with Qingdantongyu Decoction and contrast group (30 cases) with Antibiotics were set up randomly. After the two treatments lasting for ten days, a comprehensive analysis of the effects was made through the symptom, body signs, tongue condition, pulse condition.The result turns o