双源ct肺动脉造影与肺灌注成像诊断肺栓塞的对比分析-comparative analysis of shuang yuan ct pulmonary angiography and pulmonary perfusion imaging in diagnosis of pulmonary embolism.docxVIP
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双源ct肺动脉造影与肺灌注成像诊断肺栓塞的对比分析-comparative analysis of shuang yuan ct pulmonary angiography and pulmonary perfusion imaging in diagnosis of pulmonary embolism
中英文缩略词对照表英文缩写英文全名中文译名CTPACTpulmonaryangiographyCT肺动脉造影DSCTDualsourceCT双源CTDEPIDualenergyCTlungperfusionimaging双能量肺灌注成像PBVperfusionbloodvolume肺灌注血容量PTEpulmonarythromboembolism肺血栓栓塞症PEpulmonaryembolism栓子VTEvenousthromboembolism静脉血栓栓塞目录摘要…………………………………………………………………………………1ABSTRACT………………………………………………………………………2前言…………………………………………………………………………………4研究内容与方法……………………………………………………………………61.研究内容…………………………………………………………………61.1研究对象………………………………………………………………61.2纳入标准………………………………………………………………61.3排除标准………………………………………………………………61.4质量控制………………………………………………………………62.研究方法…………………………………………………………………62.1技术流程图…………………………………………………………62.2检查方法………………………………………………………………62.3诊断标准………………………………………………………………73.统计学处理…………………………………………………………………11结果…………………………………………………………………………………12讨论…………………………………………………………………………………15小结…………………………………………………………………………………22致谢…………………………………………………………………………………23参考文献……………………………………………………………………………24综述…………………………………………………………………………………29攻读硕士学位期间发表的学位论文………………………………………………40导师评阅表…………………………………………………………………………41双源CT肺动脉造影与肺灌注成像诊断肺栓塞的对比研究研究生:叶梅导师:木合拜提·买合苏提副教授摘要目的:评价双源CT肺动脉造影(CTPA)与双能量肺灌注成像(DEPI)在诊断肺动脉血栓中的作用。方法:连续收集我院2012年3月至2013年1月临床怀疑有肺动脉栓塞的患者130例,应用双源CT肺动脉成像双能量扫描,数据经处理后得到肺动脉血管图像(CTPA)和肺灌注图像(PBV),观察CTPA图像有无栓塞及栓塞的部位和程度,同时对PBV图像进行质量评价和分型,分析PBV图像的表现与CTPA图像及肺部异常表现的关系。用Kappa系数检验两位医师对PBV图像质量评价和分型的一致性,计算PBV图像诊断肺动脉栓塞的敏感度、特异度、阳性预测值、阴性预测值。结果:两位医师对肺灌注图像质量的分级及肺灌注图像分型的一致性极强,K值分别为0.79、0.82,P值均0.05。PBV图像诊断肺动脉栓塞的灵敏度、特异度、阳性预测值、阴性预测值分别为90.0%、9.1%、15.3%、83.3%。当肺段、亚段肺血管呈完全充盈缺损时,相应的肺灌注图像主要是肺段或亚段分布的灌注缺损为主,而当部分充盈缺损时,肺灌注图像以不均匀灌注缺损为主。本组100例DEPI显示肺段区灌注缺损而CTPA未见栓子,主要是由于肺部其他病变导致肺灌注异常。结论:双源CT肺动脉造影与双能量肺灌注成像不仅显示出栓子的部位、范围及其与管壁的关系,而且还可以反应肺组织的血流灌注状况,二者结合能够更完整的评价肺动脉栓塞。关键词:肺动脉栓塞;双源CT肺动脉造影;双能量肺灌注成像;X线计算机1DiagnosticvalueofdualenergyCTlungperfusionimagingcombinedwithCTpulmonaryangiographyinpatientswithpulmonaryembolismPostgraduate:YeMeiSupervrisor:AssociateProf.MuHebaitiAbstractObjective:ToinvestigatethediagnosticvalueofdualenergyCTlungperfusionimaging(DEPI)combinedwithCTpulmonaryangiography(CTPA)inpatientswithpulmonaryembolism.Methods:130consecutivepatientss
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