基于中医传承辅助系统对张忠德教授治疗支气管扩张症的用药规律分析.docVIP

基于中医传承辅助系统对张忠德教授治疗支气管扩张症的用药规律分析 　　[摘要] 目的 分析张忠德教授治疗支气管扩张症的用药经验、规律及组方特点。 方法 收集2014年7月～2015年6月张忠德教授于广东省中医院大德路总院、广东省中医院二沙岛分院接诊的中医疾病诊断为肺络张、西医疾病诊断为支气管扩张症的处方，将其信息录入“中医传承辅助系统（V2.5版本）”，运用规则分析、改进的互信息法、复杂系统熵聚类等数据挖掘方法，并结合专家本人校审，共同分析其用药规律。 结果 经筛选，93首方中共计出现91味中药，同时确定了各种药物的使用频次及其之间的关联规则，演化得到五味子_藕节_紫菀等核心组合16个，以及五味子_藕节_紫菀_牡丹皮_赤芍等新处方7个。 结论 运用中医传承辅助系统分析结果与专家临证用药特点基本吻合，中医传承辅助系统可用于专家临证经验分析与总结。 　　[关键词] 支气管扩张症；中医传承辅助平台；张忠德；用药规律 　　[中图分类号] R562.22 [文献标识码] A [文章编号] 1673-7210（2017）09（a）-0094-05 　　[Abstract] Objective To analyze the medication experience， medicine law and characteristics of composition of professor Zhang Zhongdes treatment of bronchodilator. Methods The medical records in General Institute of Guangdong Provincial TCM Hospital （Dade Road） and Ersha Island Branch of Guangdong Provincial TCM Hospital from July 2014 to June 2015 of Professor Zhang Zhongde s treatment of Fei Luo Zhang in TCM or bronchodilator in western medicine were collected. After entering the TCM inheritance support system （V2.5 edition）， the software integration rule analysis， improved mutual information method， complex system entropy clustering and other data mining methods were adopted to analyze drug use frequency， drug compatibility， group characteristics， combined with the experts reviews. Results A total of 93 prescriptions were analyzed and 91 Chinese medicines were found. The frequency of using various drugs and the association rules between drugs were analyzed. Sixteen core compositions， such as Fructus Schisandrae Chinensis_Nodus Nelumbinis Rhizomatis_Radix Asteris and other fifteen compositions， were evolved. And seven of core compositions， such as Fructus Schisandrae Chinensis_Nodus Nelumbinis Rhizomatis_Radix Asteris_Cortex Moutan Radicis_Radix Paeoniae Rubra and other six prescriptions， were evolved. Conclusion The results of using traditional Chinese medicine inheritance support system are consistent with the characteristics of expert clinical application， therefore， the traditional Chines