细胞型朊蛋白prpc在直肠癌中表达及临床意义-expression of cellular prion protein prpc in rectal cancer and its clinical significance.docxVIP

IV IV Abstract tive expression rate of PrPC in rectal carcinoma tissue with lymph nodes metastasis and without lymph nodes metastasis was 77.78%(28/36) and 45.83%(11/24) respec- tively. The above mentioned results indicated that the positive rate of PrPC was closely related with tumor differentiation, TNM stage and lymph node metasta- sis(P0.05). However, the expression of PrPC in rectal carcinoma was not related with sex, age, tumour location and tumor size(P0.05). Conclusion: The expression of PrPC in rectal carcinoma tissue is higher than that in rectal adenoma and normal rectal mucosa, ind