ESWAN序列与常规FSET2WI序列对脑微出血灶检出效能比较研究.docVIP

ESWAN序列与常规FSET2WI序列对脑微出血灶检出效能比较研究 　　[摘要] 目的 探讨ESWAN序列对脑多发微出血灶的检出效能。 方法 选择我院2011年1月～2012年1月收治的35例脑血管病患者。年龄58～81岁，排除存在脑出血、颅内占位、外伤、手术史等病例。利用西门子3.0 T磁共振，选择FSET2WI及ESWAN序列横断位扫描，分析统计结果。 结果 35例患者均存在多发微出血灶，以基底节/丘脑区多发，皮层及皮层下区次之，脑干和小脑区最少，差异有统计学意义（P0.01）。ESWAN序列对脑微出血灶的显示明显优于FSET2WI序列，差异有统计学意义（P0.01）。 结论 ESWAN序列对微出血敏感，有助于临床更早期发现病变，为及早治疗提供信息。 　　[关键词] ESWAN；FSET2WI；3.0T磁共振；微出血灶 　　[中图分类号] R445.2 [文献标识码] A [文章编号] 1673-9701（2015）12-0016-03 　　A comparative study of the effectiveness of ESWAN sequence and the FSET2WI for detection of intracerebral microbleeds 　　SHI Dongxing1 ZHANG Haiyu2 　　1.Department of Radiology， the First Affiliated Hospital of Henan Medical College of TCM， Zhengzhou 450000， China； 2.Department of Imaging， Ningxia Hui Autonomous Region People’s Hospital，Yinchuan 750021，China 　　[Abstract] Objective To compare the effectiveness of ESWAN sequence and FSET2WI for detection of the intracerebral microbleeds. Methods A total of 35 patients from the first affiliated hospital of henan medical college of TCM were studied，from January 2011 to January 2012.They were aged from 58 to 81 years old. Treated by ESWAN and conventional FSET2WI sequences at 3.0TMR scanner. The imaging foundings and related clinical data were analyzed. Results The brain microbleeds were found in 35 cases. Intracerebral microbleeds were much more visible by ESWAN MR images than FSET2WI MR images. The intracerebral microbleeds occurs frequently in the basal ganglia and thalamus area，occasionaly in the cortical and subcortical area，and hardly in the brainstem and cerebellum area. Conclusion ESWAN is more sensitive than conventional FSET2WI sequences in detecting the intracerebral microbleeds.The pathology can be detected in earlier period. 　　[Key words] ESWAN；FSET2WI；3.0TMRI；Intracerebral microbleeds 　　ESWAN是近年来发展的磁共振成像新技术，是一种全新的T2权重的GRE序列，其对去氧血红蛋白、含铁血黄素、脑内静脉结构、铁蛋白的沉积等高度敏感[1，2]。对脑出血性疾病，尤其是对脑内微出血（intracerebral microbleeds，IMB）的诊断方面具有较高的临床应用价值。本文通过ESWAN序列检测患者脑内多发IMB并与常规FSET2WI序列进行比较，从而为ESWAN序列的临床