D―二聚体在孕晚期及妊娠期高血压疾病检测意义.docVIP

D―二聚体在孕晚期及妊娠期高血压疾病检测意义 　　[摘要] 目的 探讨孕晚期孕妇及妊娠高血压疾病患者血浆D-二聚体含量的变化及临床意义。 方法 采用Sysmex CA6000全自动凝血分析仪分别检测该院2013年3―11月间健康非孕妇女100例、健康孕晚期临产孕妇100例、妊娠高血压患者50例的血浆D-二聚体水平。 结果 健康孕晚期临产孕妇D-二聚体水平（3.03±2.62）μg/mL、妊娠高血压疾病患者（4.10±1.60）μg/mL，血浆D-二聚体水平有着较为显著的提升，同对照组（0.32±0.23）μg/mL相比，差异有统计学意义，P0.01；而妊娠高血压疾病患者与健康临产孕妇相比较，P0.05，差异有统计学意义。 结论 妊娠晚期D-二聚体较正常成年女性高，妊娠期高血压疾病患者的D-二聚体的水平比正常怀孕妇女高，监测妊娠期高血压疾病患者和健康孕晚期临产孕妇的D-二聚体水平，有利于对血栓性疾病和弥散性血管内凝血（DIC）的早期诊断和防治。 　　[关键词] D-二聚体；孕晚期；妊娠期高血压疾病；血栓性疾病；DIC 监测 　　[中图分类号] R714.246 [文献标识码] A [文章编号] 1674-0742（2015）01（b）-0028-02 　　The significance of D-dimer to disease detection for pregnant women in the third trimester and pregnant women with gestational hypertension 　　LI Qiufen LIU Hairong FANG Dongxia 　　Department of Obstetrics， JIiaozuo Maternal and Child Health Care Hospital， Jiaozuo， Henan Province， 454000， China 　　[Abstract] Objective To investigate the changes and clinical significance of plasma D-dimer levels in the third trimester and pregnant women with gestational hypertensive. Methods Using automatic coagulation analyzer Sysmex CA6000 to detected the plasma D-dimer in 100 cases of the healthy non-pregnant women， 100 cases of healthy pregnant women in the third trimester labor， 50 cases of patients with gestational hypertension with between March 2013-November 2013 in our hospital. 　　Results D-dimer levels of healthy pregnant women in the third trimester labor （3.03 ± 2.62） μg / ml， D-dimer levels of patients with gestational hypertensive （4.10 ± 1.60） μg / ml， plasma D-dimer levels were significantly increased compared with the control group（0.32 ± 0.23） μg / ml， the difference There was statistically significant（p 0.01）； healthy pregnant women in labor compared with gestational hypertension patients， the difference was statistically. Conclusion D-dimer in late pregnancy is higher than normal adult females.； D-dimer levels？ of patients with gestational hypertensive is higher than normal pregnant women； It is conducive to Monitor D-dimer levels of