中医定向透药疗法治疗慢性咳嗽临床观察.docVIP

中医定向透药疗法治疗慢性咳嗽的临床观察 　　【摘要】目的： 探讨中医定向透药疗法治疗主要表现为上气道咳嗽综合征（UACS）的慢性咳嗽的临床效果。方法： 将138例来我院耳鼻喉科就诊的UACS慢性咳嗽患者按随机数字表法分为治疗组和对照组各69例。2组均口服氯雷他定1周，鼻腔吸人糖皮质激素1月。治疗组在此基础上加用中医定向透药治疗仪辅助治疗，隔天1次，连续5次，对照组不予药物导入治疗。结果： 两组治疗前后，咳嗽程度、鼻部症状和体征、咽部症状方面均明显改善；组间比较，除鼻部症状外，咳嗽和咽部症状治疗组评分明显低于单纯药物治疗对照组，统计学分析呈显著性差异（P 0.05）。临床疗效治疗组总有效率（89.9%）明显高于单纯药物治疗对照组（76.8%），统计学分析呈显著性差异（P =0.033）。结论：在西医常规治疗基础上加用中医定向透药疗法治疗慢性咳嗽能显著改善患者症状，提高其生活质量，值得推广。 　　【关键词】 中医定向透药疗法；慢性咳嗽；上气道咳嗽综合征 　　[Abstract] Objective： To evaluate the clinical efficacy of Chinese medicine targeted transdermal therapy for treating upper airway cough syndrome （UACS）， a main manifestation of chronic cough. Methods： A total of 138 patients who were diagnosed with UACS at the Department of Ear Nose and Throat （ENT） were randomly divided into the treatment group and the control group （69 patients per group）. Both groups received oral loratadine for 1 week， and nasal inhalation of glucocorticoid for 1 month. In addition to these， the treatment group also received Chinese medicine targeted transdermal therapy as an adjuvant therapy once every 2 days， for a total of 5 times. The control group was not treated with any additional drugs. Results：The severity of coughing， nasal symptoms， pharyngeal symptoms and physical signs were significant improved in both groups following treatment. Besides nasal symptoms， coughing and pharyngeal symptoms were significantly lower in the treatment group compared to the drug therapy control group （P 0.05）. In addition， the total clinical efficacy was significantly higher in the treatment group （89.9%） than the drug therapy control group （76.8%） （P=0.033）. Conclusions： The addition of Chinese medicine targeted transdermal therapy on the basis of conventional treatment can significantly improve the symptoms of chronic coughing and enhance patients’ quality of life， and therefore should be widely promoted as an adjuvant treatment for chronic coughing. 　　[Key words] Chinese medicine targeted transdermal therapy； chronic coughin