乳腺癌超声与增强MRI应用ROC曲线对比研究.docVIP

乳腺癌的超声与增强MRI应用ROC曲线对比研究 　　【摘要】 目的：对比研究乳腺彩超（US）和乳腺磁共振（MRI）增强扫描在乳腺癌的诊断价值。方法：回顾性分析广西壮族自治区人民医院收治的160例乳腺肿物患者的资料，所有患者术前均需行US、MRI增强检查，术后常规行病理检查。应用Medcal软件对影像资料进行ROC曲线分析，比较US和增强MRI诊断乳腺癌的准确性。结果：160例患者中，乳腺癌64例，其中浸润性导管癌50例，浸润性小叶癌10例，导管内癌4例，其余96例均为良性病变。US检出肿块129例，发现钙化35例，同侧腋窝淋巴结发现肿大58例；MRI增强扫描检出肿块134例，发现钙化31例，同侧腋窝淋巴结发现肿大28例。时间-信号强度曲线27例呈Ⅱ型曲线，29例呈Ⅲ型曲线。ROC曲线分析US曲线下面积（AUC）为0.897，增强MRI的AUC为0.929，两者比较差异有统计学意义（P0.05）。结论：US是乳腺癌的首选检查方法，但增强MRI在诊断乳腺癌上比US有更高的敏感性，能更多地显示乳腺癌病灶的特征，两者结合应用可以提高乳腺癌的诊断正确率。 　　【关键词】 乳腺癌； 超声； 磁共振成像； ROC曲线分析 　　Contrast Study of Ultrasonography and Contrast-enhanced MRI on Diagnosis of Breast Cancer by ROC Curve Analysis/PAN Yin-hua，HUANG Yu，LI Jie-hua.//Medical Innovation of China，2017，14（11）：037-040 　　【Abstract】 Objective：To comparatively reseach the value of diagnosis of ultrasonography（US） and contrast-enhanced MRI on breast cancer.Method：The data of 160 patients with breast lump treated in Guangxi Zhuang Autonomous Region People’s Hospital were retrospectively analyzed.All cases received examination of US，contrast-enhanced MRI and pathological biopsy.ROC curve analysis of video data by Medcal software was conducted to compare the accuracy rate of diagnosis on breast cancer.Result：There were 64 cases of breast carcinoma，50 cases of infiltrating duct carcinoma，10 cases of infiltrating labular carcinoma，4 cases of intraducteal carcinoma.We detected 129 cases with mass，35 cases with calcification and 58 cases with ipsilateral axillary lymphadenopathy by US.134 cases with mass，31 cases with calcification and 28 cases with ipsilateral axillary lymphadenopathy were detected by contrast-enhanced MRI.There were 27 cases for type Ⅱ of time-signal intensity curve and 29 cases were type Ⅲ.AUC of US was 0.897 and AUC of contrast-enhanced MRI was 0.929，there was statistical significance（P0.05）.Conclusion：US is the first choice of examination for breast cancer，but enhanced MRI in the diagnosis of breast cancer has a higher sensitivity compared with US，which shows more chara