同型半胱氨酸超敏C―反应蛋白含量与颈动脉内中膜厚度联合检测在冠心病患者中应用效果分析.docVIP

同型半胱氨酸超敏C―反应蛋白含量与颈动脉内中膜厚度联合检测在冠心病患者中应用效果分析 　　[摘要] 目的 探讨同型半胱氨酸（HCY）、超敏C-反应蛋白（Hs-CRP）含量与颈动脉内中膜厚度（IMT）联合检测在冠心病患者中的应用效果。方法 方便选取至该院就诊的150例冠心病患者（2014年2月―2017年2月）设置为实验组，另外同期选择150名健康体检人群设置为常规组，分析不同分组的HCY、Hs-CRP、IMT。结果 实验组HCY、Hs-CRP、IMT检测值分别为（20.58±5.33）μmol/L、（11.59±5.30）mg/L、（1.35±0.40）mm，相比常规组均明显较高（P0.05）；AMI患者的HCY、Hs-CRP、IMT检测值分别为（20.63±3.10）μmol/L、（16.98±2.88）mg/L、（1.61±0.35）mm，相比其他两组均明显较高（P0.05），UAP患者的HCY、Hs-CRP检测值分别为（17.30±3.25）μmol/L、（13.61±3.15）mg/L，相比SAP患者均明显较高（P0.05）。结论 HCY、Hs-CRP水平与冠心病患者的病情息息相关，随着患者病情的加剧，其检测值将会递增，便于为疾病的诊断提供相关的依据。 　　[关键词] 同型半胱氨酸；超敏C-反应蛋白；颈动脉内中膜厚度；冠心病 　　[中图分类号] R541 [文献标识码] A [文章编号] 1674-0742（2017）12（b）-0042-03 　　[Abstract] Objective To study the application effect of combined test of homocysteine， High sensitive C-reactive protein and carotid intima-media thickness in patients with coronary heart disease. Methods 150 cases of patients with coronary heart disease diagnosed in our hospital from February 2014 to February 2017 convenient selected were selected as the experimental group， while 150 cases of healthy physical examination people at the same period were selected as the routine group， and the HCY， Hs-CRP， IMT of each group were analyzed. Results The HCY， Hs-CRP， IMT test values in the experimental group were respectively （20.58±5.33）μmol/L，（11.59±5.30）mg/L，（1.35±0.40）mm， which were obviously higher than those in the control group（P0.05）， and the HCY， Hs-CRP， IMT test values of AMI patients were respectively （20.63±3.10）μmol/L， （16.98±2.88）mg/L， （1.61±0.35）mm， which were obviously higher than those in the other two groups（P0.05）， and the HCY， Hs-CRP of UAP patients were respectively （17.30±3.25）μmol/L，（13.61±3.15）mg/L， which were obviously higher than those of SAP patients（P0.05）. Conclusion The HCY and Hs-CRP levels are closely related to the diseases of patients with coronary heart disease， with the increase of the disease， the test value is increasing， and it can provide relevant basis for the diagnosis of diseases. 　　[Key words] Hom