卡前列甲酯联合缩宫素预防妊娠高血压疾病剖宫产术后出血临床研究.docVIP

卡前列甲酯联合缩宫素预防妊娠高血压疾病剖宫产术后出血临床研究 　　[摘要] 目的:观察卡前列甲酯(卡孕栓)联合缩宫素对妊娠高血压疾病(妊高征)剖宫产术中、术后出血的预防效果。方法:选择住院剖宫产分娩妊高征患者200例,随机分为缩宫素组100例,卡孕栓+缩宫素组100例,观察两组给药后术中、术后2 h出血量的差异及血压的变化。结果:术中、术后2 h出血量、产后出血的发生率,卡孕栓组明显少于对照组(P0.05)。结论:卡孕栓+缩宫素预防妊高征剖宫产术中、术后出血,安全、方便,且疗效显著。 　　[关键词] 卡前列甲酯;妊娠高血压疾病;剖宫产;预防出血;临床研究 　　[中图分类号] R714.46+1[文献标识码]A[文章编号]1673-7210(2009)07(b)-035-02 　　 　　Clinical research on the preventive effect of carboprost methylate combined with oxytocin on lying-in hemorrhage after uterine-incision delivery of women with pregnancy-induced hypertension syndrome 　　LIU Jinrong, YANG Weilan,YANG Ximing,ZHANG Ling,ZHOU Jin 　　(Department of Gynecology and Obstetrics, Maternity and Child Health Hospital,Tengzhou 277500,China) 　　[Abstract] Objective: To evaluate the preventive effect of carboprost methylate combined with oxytocin in the treatment of lying-in hemorrhage during and after uterine-incision delivery of woman with pregnancy-induced hypertension syndrome(PTH).Methods:200 cases of lying-in women with PTH were randomly divided into two groups:100 cases treated with oxytocin only(observation group),and another 100 cases treated with both carboprost methylate and oxytocin(control group). After the treatment, the difference of hemorrhage and variation of blood pressure of two groups during and two hours after uterine-incision delivery were observed and analyzed. Results: Compared with control group, both the incident rate of postpartum hemorrhage and the amount of hemorrhage of observation group were evidently smaller(P0.05).Conclusion: Its quite safe, efficient and convenientfor carboprost methylate combined with oxytocin in the prevention of hemorrhage during and after uterine-incision delivery of lying-in women with PTH. 　　[Key words] Carboprost methylate; PTH; Uterine-incision delivery; Prevention from postpartum hemorrhage; Clinical research 　　 　　产后出血目前仍是我国孕产妇死亡原因之首,而产后出血是妊娠高血压疾病(简称妊高征)的常见并发症。妊高证是一种常见的妊娠合并征,是造成产妇死亡的重要原因,我国妊高征发生率为7%~12%[1],妊高征产后出血是由于各种原因所导致的子宫收缩乏力而引起的,而宫缩乏力