单唾液酸四己糖神经节苷脂在改善脑梗死患者神经功能缺损情况中应用价值.docVIP

单唾液酸四己糖神经节苷脂在改善脑梗死患者神经功能缺损情况中应用价值 　　[摘要]目的 探讨单唾液酸四己糖神经节苷脂在改善脑梗死患者神经功能缺损情况中的应用价值。方法 选择2013年12月～2015年12月本院收治的80例脑梗死患者作为研究对象，随机分为对照组和治疗组，各40例。对照组在常规治疗方案的基础上采用吡拉西坦治疗，治疗组在常规治疗方案的基础上采用单唾液酸四己糖神经节苷脂治疗。比较两组的治疗效果、治疗前后脑神经功能缺损程度评分的改善幅度、脑神经功能指标恢复正常的时间和治疗总时间及不良反应发生率。结果 治疗组的总有效率为92.5%，显著高于对照组的72.5%，差异有统计学意义（P0.05）。两组治疗后的脑神经功能缺损程度评分显著低于治疗前，差异有统计学意义（P0.05）。治疗组治疗后的脑神经功能缺损程度评分显著低于对照组，差异有统计学意义（P0.05）。治疗组的脑神经功能恢复正常时间和治疗总时间显著短于对照组，差异有统计学意义（P0.05）。治疗组的不良反应发生率显著低于对照组，差异有统计学意义（P0.05）。结论 单唾液酸四己糖神经节苷脂在改善脑梗死患者神经功能缺损情况中的应用效果显著。 　　[关键词]单唾液酸四己糖神经节苷脂；脑梗死；治疗；神经功能 　　[中图分类号] R743.3 [文献标识码] A [文章编号] 1674-4721（2016）07（b）-0135-03 　　[Abstract]Objective To explore the application value of monosialotetrahexosyl ganglioside in improving nerve function defect in patients with cerebral infarction.Methods 80 cases of cerebral infarction in our hospital from December 2013 to December 2015 were selected and randomly divided into the control group and the treatment group，40 cases in each group.The control group was treated with pyrazole raschig on the basis of the routine treatment，the treatment group was treated with monosialotetrahexosyl ganglioside on the basis of the routine treatment.The treatment effect，improvement degree of brain nerve function defect score before and after treatment，the time of brain nerve function index return to normal and total treatment time，the incidence rate of adverse reaction in the two groups was compared respectively.Results The total effective rate in the treatment group was 92.5%，which was higher than 72.5% in the control group，with significant difference （P0.05）.The score of brain nerve function defect after treatment in the two groups was lower than that before treatment，with significant difference （P0.05）.The score of brain nerve function defect after treatment in the treatment group was lower than that in the control group after treatment，with significant difference （P0.05）.The time of brain nerve function index return to normal and total treatment time in the treatme