复方樟柳碱两种注射方法治疗视网膜中央静脉阻塞比较.docVIP

复方樟柳碱两种注射方法治疗视网膜中央静脉阻塞比较 　　[摘要] 目的 比较颞浅动脉旁皮下注射和球后注射复方樟柳碱治疗视网膜中央静脉阻塞的临床效果和护理措施。方法 方便选取2015 年1月―2016年6月该院眼科门诊确诊的73例缺血性视网膜中央静脉阻塞患者在激光治疗的同时应用复方樟柳碱辅助治疗，按随机数字表分为2组，36例采用颞浅动脉旁皮下注射，37例采用球后注射。对两组的病例作视力、FFA检查、注射NRS评分、不良反应的对比。 结果 治疗后颞浅动脉旁皮下注射组NRS评分较球后注射组低，比较差异有统计学意义（P0.05）。 结论 颞浅动脉皮下注射复方樟柳碱治疗缺血性视网膜中央静脉阻塞，与球后注射给药有相当的疗效，且患者的疼痛程度低，不良反应较少。 　　[关键词] 复方樟柳碱；视网膜中央静脉阻塞；皮下；颞浅动脉 　　[中图分类号] R473 [文献标识码] A [文章编号] 1674-0742（2016）10（b）-0143-04 　　[Abstract] Objective Comparison of clinical effect and nursing experience was injected subcutaneously around superficial temporal artery and retrobulbar injection of compound anisodine in the treatment of central retinal vein occlusion. Methods Convenient selection January 2015 to June 2016 in our hospital outpatient diagnosis of 73 cases of ischemic central retinal vein obstruction patients in laser treatment and application of compound anisodine adjuvant therapy， according to the random number table is divided into 2 groups and 36 patients with para temporal superficial artery subcutaneous injection， 37 cases with retrobulbar injection. Visual acuity， FFA examination， NRS score and adverse reaction were compared between the two groups. Results After treatment， numeric rating scales of the patients with Compound Anisodine subcutaneous injection near the temporal superficial artery were significantly lower than the retrobulbar injection group（P0.05）. Conclusion Subcutaneous Injection near the temporal superficial artery with Compound Anisodine has the same therapeutic effect as retrobulbar injection on CRVO， though with lower pain degree and the fewer side reactions. 　　[Key words] Compound anisodine；Central retinal vein occlusion； Subcutaneous ； Temporal superficial artery 　　视网膜中央静脉阻塞（central retinal vein occlusion，CRVO） 是眼科多见的严重视网膜血管性疾病，患病率在30岁以上的患者占0.3%～0.5%。CRVO以视网膜静脉迂曲扩张、出血、水肿渗出为特点，视力损害主要取决于阻塞与黄斑水肿的程度[1]。樟柳碱是从茄科植物唐古特山莨菪中分离出来的一种生物碱，作用机制与阿托品类药物相似，其复方制剂具有减轻眼血管痉挛和改善血管舒缩的功能[2]。该院于2015 年1月―2016年6月近四年来到该院眼科门诊确诊的患者73例为研究对象，分别应用颞浅动脉旁注射和球后注射复方樟柳碱治疗缺血性