大剂量雌激素联合球囊子宫支架对宫腔粘连治疗效果提高比较分析.docVIP

大剂量雌激素联合球囊子宫支架对宫腔粘连治疗效果提高比较分析 　　摘要：目的 观察分析大剂量雌激素联合球囊子宫支架治疗子宫腔粘连（IUA）的效果。方法 80例IUA患者随机分为观察组和对照组，各40例。两组患者均实施宫腔粘连电切术（TCRA）治疗，观察组术后应用大剂量补佳乐（5mg/次）口服联合球囊子宫支架治疗，对照组术后予以常规剂量补佳乐（2mg/次）联合人工周期治疗，对比两组的临床疗效。结果 术后1、2、3个月，观察组的月经量较对照组显著提高（P0.05）；术后3个月，观察组的IUA率为12.50%，显著低于对照组的47.50%（P0.05）；观察组的综合总有效率为100%，显著高于对照组的82.50%（P0.05）。结论 对IUA应用大剂量雌激素配合球囊子宫支架治疗可提高临床疗效，缓解IUA症状，促进病情康复。 　　关键词：宫腔粘连；球囊子宫支架；雌激素；大剂量；人工周期 　　Comparative Analysis of the Effect of High Dose Estrogen Combined with Balloon Stent in the Treatment of Intrauterine Adhesions 　　LIU Juan 　　（Department of Gynecology，Xinan gynecological hospital，Chengdu 610000，Sichuan，China） 　　Abstract：Objective To observe and analyze the effect of large-dose estrogen combined with balloon endometrial bracket for the treatment of ntrauterine adhesions（IUA）.Methods 80 patients with IUA were randomly divided into observation group and control group，40 cases in each.All patients underwent transcervical resection of adhesion（TCRA）treatment，the observation group received high-dose progynova（5mg/times）combined with balloon endometrial bracket，the control group received conventional-dose progynova（2mg/times）combined with artificial cycle therapy，the clinical efficacy between the two groups were compared.Results 1，2，3months after operation，the menstrual flow of observation group was significantly increased than the control group（P0.05）；After 3 months，the IUA rate of observation group was 12.50%，significantly lower than the of 47.50%control group（P0.05）；The comprehensive total effective rate of observation group was 100%，significantly higher than the 82.50%in control group（P0.05）.Conclusion The application of large-doses estrogen with balloon endometrial bracket for the treatment of IUA can improve the clinical efficacy，relieve IUA symptoms and promote disease rehabilitation. 　　Key words：Intrauterine adhesions；Balloon endometrial bracket；Estrogen；High-dose；Artificial cycle 　　子宫腔粘连（IUA）是指由多因素导致子宫内膜损伤而诱发的子宫壁组织粘连，患者常表现为腹痛、月经量减少、闭经、不孕症等，严重影响女性的身心健