奥曲肽联合泮托拉唑治疗胃十二指肠溃疡出血临床疗效探讨.docVIP

奥曲肽联合泮托拉唑治疗胃十二指肠溃疡出血临床疗效探讨 　　[摘要] 目的 研究分析奥曲肽联合泮托拉唑治疗胃十二指肠溃疡出血的临床疗效。方法 回顾性分析该院于2012年12月―2014年2月收治的100例胃十二指肠溃疡出血患者的病历资料，随机的分为对照组和治疗组，对照组和治疗组各50例，对照组患者采取泮托拉唑治疗，治疗组患者采取奥曲肽联合泮托拉唑治疗，对比分析两组患者的止血效果、临床疗效和不良反应情况。 结果 治疗组患者治疗1 d后止血效果明显优于对照组，P0.05，差异无统计学意义。治疗组患者的临床总有效率明显大于对照组，P0.05，治疗组患者不良反应发生率小于对照组，P0.05。结论 胃十二指肠溃疡出血患者实施奥曲肽联合泮托拉唑治疗，有较好的止血效果和较少的不良反应，临床疗效显著，有一定的安全性和可行性，值得临床推广应用。 　　[关键词] 奥曲肽；泮托拉唑；治疗；胃十二指肠溃疡出血；疗效 　　[中图分类号] R573.2 [文献标识码] A [文章编号] 1674-0742（2015）06（a）-0099-02 　　Clinical Curative Effect of Octreotide Combined with Pantozol in Treatment of Bleeding Gastroduodenal Ulcer 　　SUN Shao-wei， BI Yong-hui 　　Department of Gastrointestinal Surgery， Weihai Municipal Hospital， Weihai， Shandong Province， 264200 China 　　[Abstract] Objective To study the clinical curative effect of octreotide combined with pantozol in treatment of bleeding gastroduodenal ulcer. Methods Medical records of 100 cases of gastric duodenal ulcer hemorrhage patients admitted to our hospital from December 2012 to February 2014 were retrospectively analyzed and randomly divided into control group and treatment group， 50 cases in control group patients taking panxi tora azole treatment， the treatment group patients taking the octreotide combined with panxi tora azole treatment. Hemostatic effect of two groups of patients， clinical efficacy and adverse reactions were compared. Results The treatment group patients after treatment of 1 d hemostatic effect was obvious due to the control group，P 0.05， no significant difference. The clinical total effective rate of treatment group patients was significantly greater than the control group， P 0.05. The treatment group patients incidence of adverse reaction was less than the control group，P 0.05）. Conclusion Octreotide combined with diazepam tora azole treatment for patients with gastroduodenal ulcer bleeding， has good hemostatic effect， fewer adverse reactions， distinct effect ，certain feasibility and security， so it is worthy of clinical popularization and