妊娠期高血压疾病患者血清25―羟基维生素D水平临床研究.docVIP

妊娠期高血压疾病患者血清25―羟基维生素D水平临床研究 　　[摘要] 目的 妊娠期高血?杭膊』颊哐?清25-羟基维生素D水平的临床研究。 方法 选取2015年3月～ 2017年3月收治的孕产妇800例，将所有患者分为妊娠期高血压组、轻度子痫前期组、重度子痫前期组、慢性高血压并发子痫前期组和对照组，对比分析不同组别患者血清25-羟基维生素D水平，分析其对妊娠期高血压病症的影响。 结果 对照组患者血清25-羟基维生素D水平明显高于妊娠高血压疾病患者（t=3.0763，P=0.0022），轻度子痫前期组患者血清25-羟基维生素D水平高于重度子痫前期组（t=2.7951，P=0.0079），慢性高血压并发子痫前期组血清25-羟基维生素D水平最低，与对照组相比（t=9.2145，P=0.0000）、妊娠期高血压组相比（t=5.8904，P=0.0000）、轻度子痫前期组相比（t=4.8799，P=0.0000），差异均具有统计学意义。 结论 血清25-羟基维生素D水平与妊娠期高血压疾病的关联性较强，妊娠期高血压疾病风险的增高与维生素D摄入不足息息相关，因此，孕产妇应及时补充维生素D，能够有效预防妊娠期高血压疾病的发生。 　　[关键词] 孕妇；妊娠期高血压疾病 ；25-羟基维生素D；血清钙 　　[中图分类号] R714.246 [文献标识码] A [文章编号] 2095-0616（2017）20-95-03 　　Clinical study of serum 25- hydroxy vitamin D levels in patients with hypertensive disorder complicating pregnancy 　　SU Lifang LI Yudi YANG Shumiao LI Guoxia LUN Jin 　　The Peoples Hospital of Yingde City，Yingde 513000， China 　　[Abstract] Objective To explore the clinical study of serum 25- hydroxy vitamin D levels in patients with hypertensive disorder complicating pregnancy. Methods From March 2015 to March 2017， 800 cases of pregnant and parturient women were selected，and all patients were divided into gestational hypertension group， mild preeclampsia group， severe preeclampsia group， chronic hypertension complicated by preeclampsia group and the control group， the serum 25-hydroxy vitamin D levels of patients in different groups were compared and analyzed，and its influence on gestational hypertension disease were analyzed. Results The 25 - hydroxy serum vitamin D level of patients in control group were significantly higher than patients with pregnancy-induced hypertension disease（t=3.0763，P=0.0022）， the 25 - hydroxy serum vitamin D level of patients in mild preeclampsia group were higher than patients in severe preeclampsia group （t=2.7951，P=0.0079）， the 25 - hydroxy serum vitamin D level of patients in chronic hypertension complicated by preeclampsia group were minimum， compared with the control group （t=9.2145，P=0.0000）， gestational hypertension group （t=