洛赛克联合去甲肾上腺素治疗脑血管病应激性溃疡疗效评价.docVIP

洛赛克联合去甲肾上腺素治疗脑血管病应激性溃疡疗效评价 　　[摘要] 目的 评价洛赛克联合去甲肾上腺素治疗脑血管病应激性溃疡的临床价值。 方法 选取我院2008年4月～2011年5月收治的63例脑血管病应激性溃疡患者，随机将其分为两组，观察组31例采用洛赛克联合去甲肾上腺素治疗，对照组32例采用单纯洛赛克治疗，观察两组患者的治疗总有效率。 结果 观察组显效24例，有效5例，无效2例，治疗总有效率为93.54%；对照组显效20例，有效3例，无效9例，总有效率为71.88%，两组治疗总有效率比较，差异具有统计学意义（χ2=5.13，P 0.05）。 结论 洛赛克联合去甲肾上腺素治疗能有效改善脑血管病应激性溃疡患者的临床症状，减轻患者痛苦。 　　[关键词] 洛赛克；去甲肾上腺素；脑血管病应激性溃疡 　　[中图分类号] R573.1 [文献标识码] B [文章编号] 1673-7210（2012）02（c）-0162-02 　　 　　The effect evaluation of the treatment of Losec combined Norepinephrine for cerebrovascular disease stress ulcer 　　CHENG Xiaoqun 　　Department of Medical, Futian Traditional Chinese Medicine Hospital of Shenzhen City, Guangdong Province, Shenzhen 518034, China 　　[Abstract] Objective To evaluate the effect value of the treatment of Losec combined Norepinephrine for cerebrovascular disease stress ulcer. Methods 63 cases of patients with cerebrovascular disease stress ulcer were selected in our hospital from April 2008 to May 2011, and randomly divided into two groups, 31 patients of observation group were given Losec combined Norepinephrine for treatment, 32 patients of control group were given simple Losec for treatment, the total effective rates of two groups were observed. Results There were 24 cases of markedly in observation group, 5 cases of effective, 2 cases of invalid, the total treatment effective was 93.54%; there were 20 cases of markedly in observation group, 3 cases of effective, 9 cases of invalid, the total treatment effective was 71.88%, the differences of the total effective treatment of both groups were significant (χ2=5.13, P 0.05). Conclusion The treatment of Losec combined Norepinephrine can improve cerebrovascular disease in patients with stress ulcer symptoms, reduce the suffering of patient. 　　[Key words] Losec; Norepinephrine; Cerebrovascular disease stress ulcer 　　 　　机体在应激状态下受到重症疾病、严重重创等可发生胃黏膜溃疡、糜烂及出血为特征的并发症。此类并发症称为应激性溃疡[1]。其具有发病复杂、病死率高等特点。其同时也是脑血管并发症的一部分。临床上主要表现为黑便和呕血，严重者发病时伴有丘脑、脑干、小脑等部位的脑出血及脑梗死。基底节区是脑出血的好发部位。其发生率较高，可