活血生肌膏联合穴位激光照射治疗放射性皮炎临床研究.docVIP

活血生肌膏联合穴位激光照射治疗放射性皮炎临床研究 　　【摘要】 目的：?u价活血生肌膏联合穴位激光照射治疗放射性皮炎的临床效果，探讨其临床适用性。方法：选择2013年9月-2015年9月在本院住院的首次接受放射治疗发生放射性皮炎Ⅱ度损伤的肿瘤患者60例，采用随机住院号法分为观察组和对照组，各30例。对照组采用3M皮肤保护膜联合造口粉进行治疗，观察组在应用外敷活血生肌膏的同时联合穴位激光照射进行治疗。观察两组患者治疗前后血中透明质酸（HA）、Ⅲ型前胶原含量（PC-Ⅲ）、皮脂含量、经皮水分丢失（TEWL）、角质层含水量等指标及临床效果。结果：治疗前，两组患者的HA、PC-Ⅲ、皮脂含量、TEWL、角质层含水量比较，差异均无统计学意义（P0.05）；治疗后，两组的HA、PC-Ⅲ、皮脂含量、角质层含水量均显著高于治疗前，TEWL均低于治疗前，差异均有统计学意义（P0.05）；且观察组各项数据改善情况均优于对照组，差异均有统计学意义（P0.05）。观察组的总有效率为96.7%，高于对照组的80.0%，差异有统计学意义（P0.05）。两组患者治疗期间均未出现与治疗相关的不良反应。结论：活血生肌膏联合穴位激光照射治疗放射性皮炎临床效果确切，可以较快改善皮肤屏障功能，促进皮肤修复，适合临床长期推广应用。 　　【关键词】 活血生肌膏； 穴位激光照射； 放射性皮炎； 3M皮肤保护膜； 造口粉 　　Clinical Study on the Effect of Huoxue Shengji Ointment Combined with Acupoint Laser Irradiation in the Treatment of Radiation Dermatitis/LEI Xing，LI Ting，LU Jian-hua.//Medical Innovation of China，2017，14（12）：019-022 　　【Abstract】 Objective：To analyze the effect of Huoxue Shengji Ointment combined with acupoint laser irradiation in the treatment of radiation dermatitis，and to explore its clinical applicability.Method：A total of 60 patients with stage Ⅱ radiation injury who received radiotherapy for the first time from September 2013 to September 2015 in our hospital were selected，they were divided into the observation group and the control group according to random admission number method，30 cases in each group.The control group was treated with 3M skin protective film combined with stoma powder，the observation group was treated with topical Huoxue Shengji Ointment combined with acupoint laser irradiation.The levels of hyaluronic acid（HA），type Ⅲ procollagen（PC-Ⅲ）， 　　sebum content，TEWL and water content of cuticle were measured before and after treatment in both groups.Result：There were no significant differences in HA，PC-Ⅲ，sebum content，TEWL and water content of cuticle of the two groups before treatment（P0.05）；after treatment，the levels of HA，PC-Ⅲ procollagen，sebum content and water content of cuticle of the two groups were significantly higher than those before treatment，an