布地奈德联合沙丁胺醇雾化吸入治疗儿童哮喘急性发作疗效分析.docVIP

布地奈德联合沙丁胺醇雾化吸入治疗儿童哮喘急性发作疗效分析 　　【摘 要】目的：探讨布地奈德联合沙丁胺醇雾化吸入治疗儿童哮喘急性发作的临床疗效。方法：选择92例哮喘急性发作患儿，根据入院时采用的治疗方法分为治疗组和对照组，所有患儿入院后均根据病情给予常规治疗，治疗组在常规治疗的基础上给予布地奈德混悬液1.0mg和5%硫酸沙丁胺醇溶液0.5ml雾化吸入，每日2次；对照组给予甲基强的松龙1mg/kg静脉滴注，每日1次，连续使用3天后观察两组患儿临床症状改善情况，并进行疗效评定。结果：治疗3天后，两组患儿症状有所缓解，呼吸困难、咳嗽减轻，呼吸衰竭纠正，无死亡病例。治疗组总有效率95.6%，对照组总有效率73.9%，经统计学分析（P0.01），具有显著差异。结论：布地奈德联合沙丁胺醇雾化吸入治疗儿童哮喘急性发作具有安全、使用方便、临床疗效确切、不良反应小的特点，是治疗儿童哮喘急性发作的最佳选择，值得临床推广使用。 　　【关键词】布地奈德；沙丁胺醇；甲基强的松龙；雾化吸入；儿童；哮喘 　　【中图分类号】R69 【文献标识码】A 【文章编号】1004-7484（2013）05-0048-01 　　Analysis of curative effect of the treatment of acute attack of asthma in children inhaled budesonide andsalbutamol 　　Zhong Xiuhua ，LiKe dong ，Mu RongSanqun 　　（Guangdong Province to the Municipal Peoples Hospital Department of Pediatrics） 　　（Yellow River in Henan Institute of Technology School of Medicine） 　　【Abstract】Objective：Study of inhaled budesonide combined with salbutamol in treatment of acute attack of asthma in children.Methods： 92 cases of acute asthma in children， according to the methods of treatment were used and divided into treatment group and control group， all patients after admission were given conventional treatment according to the illness， the treatment group in the conventional treatment based on the given budesonide and salbutamol sulfate solution 5% 1.0mg 0.5ml inhalation， 2 times daily； the control injection after 1mg/kg intravenous group were given methyl strong， 1 times a day， 3 days of continuous use of the two groups were observed the improvement of clinical symptoms， and the therapeutic effect was evaluated.Results：3 days after treatment， symptoms of two groups of children with ease， dyspnea， cough， respiratory failure to correct， no death case. Treatment group total effectiveness 95.6%， the comparison group total effectiveness 73.9%， statistically （P 0.01）， with significant difference.Conclusion：Effect of budesonide combined with salbutamol atomization inhalation with safety， convenient use， exact clinical curative effect， adverse reac