布地奈德联合阿奇霉素治疗小儿肺炎支原体感染临床效果分析.docVIP

布地奈德联合阿奇霉素治疗小儿肺炎支原体感染临床效果分析 　　[摘要] 目的 探讨布地奈德联合阿奇霉素治疗小儿肺炎支原体感染的临床效果。 方法 选取2015年1月～2016年2月我院收治的小儿肺炎支原体感染患儿76例，按随机数字表法分为两组，对照组38例，采取阿奇霉素治疗，观察组38例，采取雾化吸入布地奈德联合阿奇霉素治疗，治疗3周后，观察两组治疗效果及不良反应发生情况。 结果 观察组退热时间、咳嗽消失时间、喘息消失时间及肺部??音消失时间均短于对照组（P0.05）。 结论 对小儿肺炎支原体感染患儿采取布地奈德联合阿奇霉素治疗的效果较好，改善患儿临床症状，且不良反应少。 　　[关键词] 小儿；肺炎支原体感染；布地奈德；阿奇霉素；雾化吸入 　　[中图分类号] R725.6 [文献标识码] B [文章编号] 1673-9701（2017）04-0068-03 　　Analyze the clinical effect of budesonide combined with azithromycin in treatment of mycoplasma pneumoniae infection in children 　　FANG Wei 　　Department of Pediatrics，Maternity and Child Care Hospitl of Yueyang in Hunan Province，Yueyang 414000，China 　　[Abstract] Objective To investigate the clinical effect of budesonide combined with azithromycin in treatment of mycoplasma pneumonia infection in children. Methods A total of 76 cases of children with mycoplasma pneumoniae infection from January 2015 to February 2016 in our hospital were selected， they were randomly divided into two groups， with 38 cases in control group， they were treated by azithromycin， with 38 cases in observation group ， they were treated by budesonide combined with azithromycin. After three weeks’ treatment， the curative effect and adverse reaction of two groups were observed. Results Antipyretic time，cough disappear time，wheezing time and pulmonary rales disappear time of the observation group were all shorter than those of the control group （P0.05）. Conclusion The effect of budesonide combined with azithromycin in the treatment of children with mycoplasma pneumoniae infection is better， it improves the clinical symptoms， and has less adverse reactions. 　　[Key words] Pediatric pneumonia；Mycoplasma infection； Budesonide； Azithromycin； Aerosol inhalation 　　肺炎支原体感染是小儿常见疾病，发病率较高，约占儿童肺炎总人数的10%～40%，且好发于5～15岁儿童。该病常见症状有发热，热型不定，初期为刺激性咳嗽，夜间剧烈咳嗽，且常伴有头痛、咽痛症状。阿奇霉素是治疗小儿肺炎支原体感染的常用抗炎药物，但效果一般。近年有研究发现，约有5%～25%的哮喘、喘息发作与肺炎支原体感染有关[1]。而布地奈德是一种高效糖皮质激素，经雾化吸入后，具有良好的局部抗炎作用。故我院对2015年1月～2016年2月收治的38例肺炎支原体感染患儿采取布地奈德联合阿奇霉素治疗，效果较好，现报道如下。