中医“四联”疗法对急性胰腺炎临床症状及实验室指标分析-analysis of clinical symptoms and laboratory indicators of acute pancreatitis treated with.docxVIP
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中医“四联”疗法对急性胰腺炎临床症状及实验室指标分析-analysis of clinical symptoms and laboratory indicators of acute pancreatitis treated with
摘要
摘要
中医“四联”疗法对急性胰腺炎临床症状及实验室指标分析
中医“四联”疗法对急性胰腺炎临床症状及实验室指标分析
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摘 要
急性胰腺炎(acute pancreatitis,AP)是临床常见急腹症,其中轻型胰腺炎(mild acute pancreatitis,MAP)约占 AP 的 80%左右,20%-30%患者临床经过凶险,常由 轻型迅速发展成重症急性胰腺炎 SAP(severe acute pancreatitis,SAP)。重症急性胰 腺炎病情严重,并发症多,病死率高。目前 SAP 的早期积极保守治疗己成国内外 共识,现阶段的中医研究针对 SAP 不同阶段的临床表现及病理生理机制,着重中 医整体治疗,辨证论治,病证结合中医的通里攻下、清热解毒、益气 养阴及活血 化瘀等治则在全国得到了广泛的研究,中医药治疗在抑制全身炎症反应和肠道细 菌移位,改善微循环方面的作用也被逐步揭示,因而确定了中医治疗在 SAP 治疗 中的地位。
目的: 评价中医药治疗急性胰腺炎 临床疗效。 探讨中药“四联”疗法 对急性胰 腺炎的主要症状及实验室指标影响。 方法:在文献调研及专家咨询的基础上,制定统一的临床观察表,收集中医学院 一附院消化科 2004 年 6 月至 2009 年 2 月急性胰腺炎患者的住院病历共 43 例,按
纳入标准及排除标准收入本课题病例共 41 例,参照中华医学会消化病学分会胰腺
疾病学组会于 2003 年 12 月 13 日在上海召开的全国胰腺疾病学术大会上通过的
《中国急性胰腺炎诊治指南(草案)》诊断标准。通过比较治疗前后的血清淀粉酶, 白细胞,CT, 中医症状的积分改善,进行评价本法对急性胰腺炎治疗效的影响 , SAP 治疗前后并发症的改善。
结果:经治疗 7 天后,轻症急性胰腺炎 29 例治愈率,总有效率,分别为 66.6%, 92.20%,其中无效 2 例中经治疗后病情未能控制演变至急性重症胰腺炎者 1 例, 占轻症急性胰腺炎总数 7.8%。中医症状治愈率,总有效率,分别为 74.4%,100%。 治疗前后急性胰腺炎组中血白细胞、血淀粉酶、CT、的恢复对比 p0.01,SAP12 例总有效率为 91.7%。 结论:中医“四联”特色疗法治疗急性胰腺炎临床疗效显著。 关键词:急性胰腺炎;中西医结合;“四联”疗法
Analysis of Traditional Chinese Medicine Tetragenus Ttherapy of Acute Pancreatitis in Clinical Symptoms and Laboratory Indicators
Wang Gongxun (Internal Medicine of Traditional Chinese Medicine ) Directed by Zhang Zhaolan
Abstract
Acute Pancreatitis (AP) is a commonly-seen acute abdomen in the clinic, in which the mild acute pancreatitis(MAP) accounts for 80 percent of the AP; besides that, 20 to 30 percent of the patients passed through an extremely dangerous state, usually developing to severe acute pancreatitis (SAP) from light pancreatitis. The state of severe acute pancreatitis (SAP) is in a bad way, with many complications and high case fatality rate. At the present time, the conservative treatment of the SAP in its early stage has come to an agreement home and abroad. The traditional Chinese medicine at present aims at the clinical manifestation and physiopathologic mechanism in different stages of SAP, makes emphasis on the whole therapy of traditional Chinese medic
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