异甘草酸镁与复方甘草酸苷治疗慢性肝炎疗效对比研究.docVIP

异甘草酸镁与复方甘草酸苷治疗慢性肝炎疗效对比研究 　　[摘要] 目的 对比分析慢性肝炎患者采用异甘草酸镁和复方甘草酸苷治疗后的临床效果。 方法 选择2014年9月～2015年12月期间我院收治的103例慢性肝炎患者进行回顾性分析，按照治疗方法分为两组，研究组52例，采用异甘草酸镁治疗，对照组51例，采用复方甘草酸苷治疗，比较两组患者的临床疗效及肝功能。 结果 研究组的总有效率明显高于对照组，差异有统计学意义（P0.05）；治疗后两组ALT、TBIL、AST均较治疗前有明显降低，PA较治疗前有明显升高，差异有统计学意义（P0.05）；研究组治疗后ALT、TBIL、AST显著低于对照组，PA显著高于对照组，差异有统计学意义（P0.05）。 结论 异甘草酸镁及复方甘草酸苷在慢性肝炎的治疗方面均有较好的效果，但是异甘草酸镁与复方甘草酸苷比较更有优势，值得在临床推广应用。 　　[关键词] 肝炎；异甘草酸镁；复方甘草酸苷；病毒性肝炎；酒精性脂肪性肝炎 　　[中图分类号] R575.1 [文献标识码] B [文章编号] 1673-9701（2016）24-0104-03 　　[Abstract] Objective To compare the clinical effect in patients with chronic hepatitis treated with isoglycyrrhizinate magnesium and compound glycyrrhizin. Methods 103 patients with chronic hepatitis who were selected from September 2014 to December 2015 in our hospital were retrospectively analyzed， all the patients were divided into two groups according to the treatment methods， the study group（52 cases） was given isoglycyrrhizinate magnesium treatment， and the control group（51 cases） was given compound glycyrrhizin treatment. The clinical efficacy and the liver function of the two groups were compared before and after treatment. Results The total efficiency of the study group was significantly higher than that of the control group， the difference was statistically significant（P0.05）； After treatment，ALT，TBIL，AST of two groups were significantly lower than those before treatment， PA was significantly higher than those before treatment， the differences were statistically significant（P0.05）； ALT，TBIL，AST of the study group after treatment were significant lower than that of the control group，PA of the study group after treatment was significant higher than that of the control group，the differences were statistically significant（P0.05）. Conclusion Effect of isoglycyrrhizinate and magnesium compound glycyrrhizin in the treatment of chronic hepatitis is better， but isoglycyrrhizinate magnesium compound glycyrrhizin comparative advantage， it can be applied in clinical practice. 　　[Key