惊恐障碍患者心理特征和心率变异性表达及临床意义.docVIP

惊恐障碍患者心理特征和心率变异性表达及临床意义 　　[摘要]目的 探?惊恐障碍患者心理特征和心率变异性的表达及临床意义。方法 选取广东省人民医院2013年6月～2014年12月接收的惊恐障碍患者60例为研究组，另选取同时期于广东省人民医院健康体检的60例健康人员为对照组，两组均采用心理问卷调查并借助心率变异性频谱对其心率变异性进行分析、对比。结果 研究组患者均存在不同程度的焦虑，与对照组比较差异有统计学意义（P0.05）；对照组R-R间期标准差（SDNN）、间隔5 min间期标准差（SDANN）、相邻RR间期差异≥50 ms百分数（PNN50）、相邻R-R间期差值均方根（RMSSD）以及频域分析高频功率（HF）、低频功率（LF）、极低频功率（VLF），低高频功率比（LF/HF）等指标水平均高于研究组，差异有统计学意义（P0.01）。结论 惊恐障碍患者心理状态不佳，影响其心率变异性，应根据患者的实际情况采取相关措施以改善预后。 　　[关键词]惊恐障碍；心理特征；心率变异性；迷走神经；交感神经 　　[中图分类号] R395.4 [文献标识码] A [文章编号] 1674-4721（2016）11（a）-0033-04 　　Expression and clinical significance of psychological characteristics and heart rate variability in patients with panic disorder 　　LIU Xiu-li1 YANG Cheng-jia2 CHEN Li-yong3▲ 　　1.The First District of Female，Mental Hospital of Guangzhou Civil Administration Bureau in Guangdong Province，Guangzhou 510430，China；2.The First General Department，Huifu Branch of Guangdong Provincial People′s Hospital in Guangdong Province，Guangzhou 510120，China；3.The Sixth District，Mental Hospital of Guangzhou Civil Administration Bureau in Guangdong Province，Guangzhou 510430，China 　　[Abstract]Objective To discuss the expression and clinical significance of psychological characteristics and heart rate variability in patients with panic disorder.Methods Sixty patients with panic disorder treated by Guangdong Provincial People′s Hospital from June 2013 to December 2014 were selected as the study group，and another sixty healthy people for physical examination in Guangdong Provincial People′s Hospital during the same period were selected as the control group.Both the two groups were given psychological questionnaire，and the heart rate variability was compared and analyzed by heart rate variability spectrum.Results The patients in the study group had different level of anxiety，and the differences were statistically significant compared with those in the control group （P 　　[Key words]Panic disorder；Psychological characteristics；Heart rate variability；Nervi vagus；Sympathetic nerve