抗凝治疗在肺心病治疗中临床应用价值.docVIP

抗凝治疗在肺心病治疗中临床应用价值 　　【摘要】目的 探究肺心病患者采用抗凝治疗的临床效果。方法 选取本院2015年7月～2017年5月收治的肺心病患者96例，并根据双盲法分为2组，对照组与观察组分别予以常规治疗与抗凝治疗，并对比2组患者临床效果、症状消失时间、治疗时间、全血低切粘度、血浆粘度、红细胞比容、全血高切粘度、红细胞聚集指数、凝血酶原片段、纤维蛋白原、血小板膜蛋白-140、二氧化碳分压、氧分压水平以及不良反应。 　　结果 观察组患者总有效率91.67%，高于对照组的72.92%，（P0.05）；观察组患者症状消失时间与治疗时间都少于对照组（P0.05）；观察组患者全血低切粘度、血浆粘度、红细胞比容、全血高切粘度、红细胞聚集指数均低于对照组（P0.05）；?^察组患者凝血酶原片段、纤维蛋白原、血小板膜蛋白-140、二氧化碳分压都低于对照组（P0.05）；观察组患者的氧分压水平高于对照组（P0.05）；2组患者治疗期间都没有产生药物不良反应。结论 抗凝治疗在对肺心病的治疗过程中，缩短症状消失时间与治疗时间可使患者的血液流变学指标、血气指标以及凝血参数明显改善，不良反应较少，使患者的治疗效果进一步提高。 　　【关键词】抗凝治疗；肺心病；应用价值 　　【中图分类号】R541.5 【文献标识码】A 【文章编号】ISSN.2095-6681.2018.02..03 　　【Abstract】Objective To explore the clinical effect of anticoagulant therapy in patients with pulmonary heart disease.Methods 96 patients with pulmonary heart disease in our hospital from July 2015～2017 year in May according to the double blind method divided into 2 groups.Results in the observation group，the total efficiency of 91.67%， higher than 72.92% of the control group（P0.05）；patients in the observation group symptoms disappeared time and treatment time were less than the control group （P0.05）； patients in the observation group the whole blood viscosity， plasma viscosity， hematocrit，whole blood viscosity， erythrocyte aggregation index were lower than the control group （P0.05）； patients in the observation group， prothrombin fragment fibrinogen， platelet membrane protein -140， partial pressure of carbon dioxide is lower than that of the control group （P0.05）；the observation group of patients with oxygen levels higher than the control group （P0.05）； the 2 groups of patients during treatment were no adverse drug reactions.Conclusion anticoagulant therapy in the treatment of pulmonary heart disease， shorten the treatment time and the symptoms disappear time can make the patients blood rheology， blood gas index and 　　coagulation parameters improved significantly，less adverse reaction， so that the treatment effect of the patients further. 　　【Key words】Anticoagulant therapy；Pulm