探讨硫酸镁治疗中重度妊娠期高血压疾病疗效观察.docVIP

探讨硫酸镁治疗中重度妊娠期高血压疾病疗效观察 　　【摘要】 目的：探讨分析硫酸镁治疗中重度妊娠期高血压疾病的临床疗效。方法：选取本院2012年1月-2014年1月收治的妊娠期高血压疾病患者60例作为研究对象，按照随机分配原则将入选的患者分为治疗组和对照组，每组患者为30例。两组均采用硫酸镁进行治疗，但治疗组的用药剂量高于对照组，观察两组临床效果。结果：经治疗后，治疗组患者的总有效率达到了93.3%，而对照组总有效率仅有60.0%，治疗组显著高于对照组，差异具有统计学意义（P0.05）。结论：对于妊娠期高血压疾病患者采用大剂量的硫酸镁治疗中重度妊娠期高血压疾病的临床疗效显著好于常规用量硫酸镁疗效，其药物并发症等临床效果与常规剂量相同。 　　【关键词】 硫酸镁； 硝苯地平； 妊娠期高血压疾病； 临床疗效 　　【Abstract】 Objective： To discuss and analyze the clinical effect of magnesium sulphate on moderate to severe pregnancy-induced hypertension.Method： 60 patients with pregnancy-induced hypertension were selected in our hospital from January 2012 to January 2014， they were randomly divided into the treatment group and the control group，30 patients in each group. Both groups were treated with magnesium sulphate but the treatment group were treated with higher dose of magnesium sulphate than the control group.The therapeutic effect in both groups were observed. Result： The total effective rate in the treatment group was 93.3%， and 60.0% in the control group， it was higher than the control group， there was significant difference between the two groups（P0.05）. The dizzy，headache，chest congestion， palpitation and other adverse drug reactions，postpartum hemorrhage， placental abruption， premature birth and caesarean birth between the two groups were compared， the differences were statistically significant（P0.05）.Conclusion： The clinical effect of high dosage of magnesium sulphate is better than the normal dosage of magnesium sulphate， and its drug complications and clinical results are the same with normal dosage of magnesium sulphate in treating patients with moderate to severe pregnancy-induced hypertension. 　　【Key words】 Magnesium sulphate； Nifedipine； Pregnancy induced hypertension； Clinical curative effect 　　妊娠期高血压疾病在临床上属于妇女妊娠期中一种常见的并发症，病情严重时候能够导致妊娠期的妇女出现多功能紊乱，从而出现昏迷、抽搐等症状，甚至导致胎儿在腹中死亡，威胁着孕妇和婴儿的生命安全[1]。妊娠期高血压疾病在年龄40岁的产妇、有过慢性高血压疾病、肾炎糖尿病以及体型比较胖的患者中发生率比较高，且当外部环境寒冷、气温变化快以及患者精神过度紧张等都可能会使病情加重[2]。导致该病的主要病因是机体的子宫张力过高。传统在临床上