探讨曲美他嗪联合阿托伐他汀治疗冠心病稳定型心绞痛应用效果.docVIP

探讨曲美他嗪联合阿托伐他汀治疗冠心病稳定型心绞痛应用效果 　　[摘要] 目的 探讨研究曲美他嗪联合阿托伐他汀治疗冠心病稳定型心绞痛的临床效果及使用价值。 方法 将2013年4月―2017年7月间该院收治的冠心病稳定型心绞痛患者作为目标对象，方便选择符合该次研究纳入标准及排除标准的100例进行分组治疗，采用数字表法分组，共2组各50例。对照组采用曲美他嗪进行治疗，观察组则联合使用阿托伐他汀钙，对2组患者的治疗效果进行比较。 结果 治疗后观察组显示总有效率为96.0%，对照组为82.0%，对比结果提示观察组更高（χ2=5.005；P=0.025）。对比治疗前周心绞痛发作次数以及持续时间提示差异无统计学意义（t周心绞痛发作次数=0.370；P=0.712。t持续时间=0.312；P=0.756）。对比治疗后的上述指标则提示2组较之治疗前均有明显改善，但观察组改善效果更理想（t周心?g痛发作次数=5.883；P=0.000。t持续时间=5.744；P=0.000）。 结论 对冠心病稳定型心绞痛患者使用曲美他嗪以及阿托伐他汀进行治疗所得效果显著，可有效改善患者症状，故值得推广。 　　[关键词] 冠心病稳定型心绞痛；阿托伐他汀；曲美他嗪；临床效果 　　[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742（2018）02（b）-0124-03 　　[Abstract] Objective This paper tries to explore the effect of trimetazidine combined with atorvastatin for the treatment of stable angina pectoris in coronary heart disease and its use value. Methods The coronary heart disease patients with stable angina in our hospital from April 2013 to July 2017 was targeted and according to the inclusion criteria and exclusion criteria of this research 100 patients were convenient selected to be treated and grouped by digital table method to two groups which had 50 patients in each group. The patients in control group were treated by trimetazidine， while the patients in observation group were treated by trimetazidine combined with atorvastatin to made a comparison of treatment effect between the two groups. Results The observation group after treatment showed that the total effective rate was 96.0%， and the control group was 82.0%. The contrast results suggested that observation group was higher （χ2=5.005； P=0.025）. Before comparative treatment， the previous angina frequency and duration suggested no significant difference （tAngina pectoris episodes=0.370； P=0.712， tduration=0.312； P=0.756）. After comparative treatment， the index indicated that two groups after treatment were obviously improved， and the observation group had more ideal improvement （tAngina pectoris episodes=5.883； P=0.000， tduration=5.744； P=0.000）. Conclusion The effect of trimet