曲美他嗪在慢性心力衰竭患者中应用体会.docVIP

曲美他嗪在慢性心力衰竭患者中应用体会 　　[摘要] 目的 探讨曲美他嗪在慢性心力衰竭治疗中的临床效果。方法 该研究随机选取了2014年6月―2015年6月期间该院进行治疗的慢性心力衰竭患者100例作为研究对象，将所有研究对象按照所采取的治疗方式分为观察组和对照组，每组各包含了50例研究对象。两组患者在入院后均给予常规的抗心力衰竭综合治疗，观察组患者在此治疗基础上，再给予曲美他嗪进行治疗。结果 观察组患者临床治疗总有效率达到了92.0%，对照组患者仅为70.0%，组间比较差异有统计学意义（P0.05）。观察组患者治疗后，LVEF、LVEDVI、LVSAVI及E/A等各项超声心动图指标改善程度显著优于对照组患者，组间比较差异有统计学意义（P0.05）。 结论 曲美他嗪治疗慢性心力衰竭能够显著提高患者的临床治疗效果，疗效显著。 　　[关键词] 曲美他嗪；慢性心力衰竭；临床效果 　　[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742（2016）01（b）-0150-02 　　Application Experience of Trimetazidine in Patients with Chronic Heart Failure 　　QIN Hai-yan 　　Penglai Peoples Hospital， Penglai， Shandong Province， 265600 China 　　[Abstract] Objective To study the clinical effect of trimetazidine in treatment of chronic heart failure. Methods 100 cases of patients with chronic heart failure treated in our hospital from June 2014 to June 2015 were selected as the research object and divided into two groups with 50 cases in each according to the different treatment methods， both groups were given combined treatment of anti heart failure after admission， and the observation group were given additional trimetazidine treatment on the basis of the control group. Results The total treatment effective rate was 92.0% in the observation group and only 70.0% in the control group， and the difference between groups was statistically significant （P0.05）， after treatment， the improvement degree of various echocardiogram indexes of LVEF， LVEDVI， LVSAVI and E/A were obviously better than those in the control group， and the differences between groups were statistically significant （P0.05）. Conclusion Trimetazidine in treatment of chronic heart failure can obviously improve the patient’s clinical treatment effect and the curative effect is obvious. 　　[Key words] Trimetazidine； Chronic heart failure； Clinical effect 　　慢性心力衰竭是一种临床常见的内科疾病，该疾病好发于老年人群体，具有较高的致死率，对患者的生命健康具有极大的危害[1]。因此，患者一旦出现慢性心力衰竭，临床需给予积极地治疗，目前对于慢性心力衰竭的治疗，主要依靠的是药物疗法，治疗原则是“强心、利尿、扩张血管”[2]。尽管目前临床对于慢性心力衰竭的治疗进行了深入的研究，但是目前的一些抗心力衰竭药物治疗的疗效并不显著[2