有氧运动对大鼠血糖血脂和血液凝固功能影响.docVIP

有氧运动对大鼠血糖血脂和血液凝固功能影响 　　摘 要:目的:研究有氧运动(游泳)对大鼠血糖、血脂和血液凝固功能的影响。方法:30只S D大鼠进行不同强度的游泳训练后,测定其血糖、血脂、血浆组织因子(TF)活性、组织因子途 径抑制物(TFPI)抗原、组织型纤溶酶原激活物(t-PA)和纤溶酶原激活剂抑制物-1 (PAI-1)的 活性。结果:1)与对照组相比,运动对大鼠血糖有降低趋势,但差异无统计学意义(p0. 05);2) 小强度运动使大鼠血清LDL明显降低(p0.05)。结论:小强度的运动训练可以改善机体的凝血和纤溶功 能,而大强度的训练不利于改善纤溶功能;且降低机体的抗凝功能。 　　关键词:运动;大鼠;血糖;血脂;血液凝固 　　中图分类号:G804.7文献标识码:A文章编号 :1007-3612(2009)07-0066-03 　　 　　On the Effects of Aerobic exercise (Swimming) on Blood Glucose,BloodLipid and CoagulativeSystem in Rats 　　ZHANGLuo geng 　　(P.E. of Department, Changsha University ofScience Technolo gy, Changsha410076, Hunan China) 　　Abstract: Objective: The aim of thisStudy is to observe the changes of blood gl ucose, bloodLipid and coagulativeSystem of rats after aerobic-exercise (Swimmi ng). Method:30Sprague-Dawley male rats are randomly divided into three groups,taking part in different intensitiesSwimming trainings. The content of blood gLucose, bloodLipid, the activity of plasma t-PA, PAI-1, the antigen contents ofTF and TFPI are measured. Results:1) Comparing with the control group, the con tent of blood glucoseShowsLittle decrease in aerobic-exercise group (p0.05);2) Compared with the control,LDL decreases evidently inLow intensitySwimm ing training group(p0.05) and increases in high intensitySwimming traininggroup;3) HDL increases inLow intensitySwimming training group, but decreasesevidently in high intensitySwimming training group;4)Low intensitySwimmingtraining maySignificantly increase t-PA activity and ratio of t-PA to PAI-1(p 0.01),and reduce PAI-1 activity(p0.05). High intensitySwimming trainin g increases PAI-1 activity and does not change t-PA activity. TheSwimming train ing may increase the antigen concentration of TFPI, and high intensitySwimmingtraining may increase plasm TFPI concentration(p0.05) and the ratio of TFPItoTF(p0.01),and high intensitySwimming trainingSignificantly increases ant igen concentration of TF, but does not change the ratio of TFPI to TF. Conclusio n:Low intensit