氨氯地平联合厄贝沙坦对糖尿病合并高血压疗效及对QT离散度影响.docVIP

氨氯地平联合厄贝沙坦对糖尿病合并高血压疗效及对QT离散度影响 　　【摘要】 目的：探讨氨氯地平联合厄贝沙坦对糖尿病合并高血压的疗效，并分析其对QT离散度的影响。方法：回顾性分析2015年2月-2017年2月本院门诊收治的104例糖尿病合并高血压患者的临床资料，其中单纯接受厄贝沙坦治疗的34例为A组，单纯接受氨氯地平治疗的34例为B组，氨氯地平联合厄贝沙坦治疗的36例为C组。治疗结束后评价三组的疗效，观察治疗前后三组患者血糖、血压的变化情况，同时比较三组患者治疗前后QT离散度的变化。结果：A、B、C三组临床治疗总有效率分别??82.35%、88.24%、100%，C组显著高于A、B两组，差异均有统计学意义（P0.05）。三组治疗后血糖、血压各项指标较治疗前均有显著改善，C组改善情况均显著优于A、B两组，B组降压效果显著优于A组，差异均有统计学意义（P0.05），治疗后C组低于A、B两组，差异均有统计学意义（P0.05）。结论：氨氯地平联合厄贝沙坦治疗糖尿病合并高血压的效果较好，不但能维持稳定的血糖水平，有效降压，更能帮助改善患者左心室肥厚情况，值得推广。 　　【关键词】 氨氯地平； 厄贝沙坦； 糖尿病； 高血压； QT离散度 　　Effects of Amlodipine Combined with Irbesartan on Diabetes Mellitus Combined with Hypertension and Its Effect on QT Dispersion/LIU Yi.//Medical Innovation of China，2017，14（35）：005-008 　　【Abstract】 Objective：To investigate the effect of Amlodipine combined with Irbesartan on diabetes mellitus combined with hypertension and its effect on QT dispersion.Method：The clinical data of 104 cases of diabetes with hypertension treated in our hospital from February 2015 to February 2017 were retrospectively analyzed，which only received Irbesartan treatment of 34 cases of group A，simply receiving Amlodipine treatment of 34 cases of group B，Amlodipine combined with Irbesartan treatment of 36 cases of group C.After treatment，the curative effects of three groups were evaluated，and the changes of blood glucose and blood pressure were observed before and after treatment.At the same time，the changes of QT dispersion before and after treatment were compared.Result：The total effective rate of clinical treatment was 82.35%，88.24% and 100% in group A，B and C，group C was higher than those of group A and B，the differences were statistically significant（P0.05）.The blood glucose and blood pressure of three groups were significantly improved compared with those of before treatment，the improvement of group C was significantly better than those of group A and B，the antihypertensive effect of group B was significantly better than that of group A，the difference was statistically s