济南市PM2.5与人体相关疾病发病率关联性研究.docVIP

济南市PM2.5与人体相关疾病发病率关联性研究 　　[摘要] 目的 研究济南市空气中PM2.5与临床呼吸科、心内科和神经内科门诊量的关系。 方法 收集济南市两家综合性医院一年呼吸科、心内科和神经内科门诊量、空气质量及气象数据，在控制“星期几效应”、气象因素等混杂因素的基础上，运用广义相加泊松回归模型分析了PM2.5对其的影响。 结果 在两日累积PM2.5小于200 μg/m3时，随着PM2.5的增加，呼吸科门诊量增加并不大，当其大于200 μg/m3且小于400 μg/m3时，门诊量增加较大，大气中PM2.5浓度与呼吸科日门诊量间存在非线性关系。两日累积PM2.5浓度与心内科和神经内科门诊量呈线性关系，两日累积PM2.5每增加1 μg/m3，两医院心内科、神经内科门诊量大约增加1例患者。 结论 随着空气中PM2.5浓度的增加，临床呼吸科、心内科和神经内科门诊量有增加趋势，但PM2.5浓度与不同科室日门诊量关系稍有不同。 　　[关键词] PM2.5；临床常见疾病；广义可加模型 　　[中图分类号] R195.1 [文献标识码] B [文章编号] 1673-9701（2015）16-0114-04 　　[Abstract] Objective To study the connections between PM 2.5 in the air in Jinan city and the outpatient visits in the department of pneumology， the department of cardiology and the department of neurology. Methods Outpatient visits in the department of pneumology， department of cardiology and department of neurology in two comprehensive hospitals in Jinan， air quality and meteorological data were collected. On the basis of controlling confounding factors such as day of the week and meteorological data， generalized additive poisson regression model was applied to analyze the effect of PM 2.5 on the outpatients visits. Results While two-day cumulative PM 2.5 was lower than 200 μg/m3， the increase of outpatients visits in the department of pneumology was not substantial along with the increase of PM 2.5. While PM 2.5 was higher than 200 μg/m3 and lower than 400 μg/m3， the outpatient visits were large. Concentration of PM 2.5 in the atmosphere showed a non-linear connection with daily outpatients visits in the Department of Pneumology. Concentration of two-day cumulative PM 2.5 showed a linear connection with the outpatient visits in department of cardiology and department of neurology. Once the two-day cumulative PM 2.5 increased 1 μg/m3， 1 more patient visited the outpatient of department of cardiology and department of neurology. Conclusion With the increase of PM 2.5 concentration in the air， outpatient visits in the department of pneumology， the department of car