生化检查对人工髋关节感染诊断价值.docVIP

生化检查对人工髋关节感染诊断价值 　　[摘要] 目的 评价分析使用血沉及CRP两指标诊断筛选人工髋关节感染的临床应用价值，为临床推广应用提供依据。方法 回顾分析2013年11月―2015年3月间患者的临床症状、体征、所患疾病史等。结果146例采用人工髋关节翻修术进行治疗的患者中，人工髋关节感染的19例患者中，11例血沉检测为阳性，8例阴性；13例CRP阳性，6例阴性，血沉检测阳性合并CRP阴性患者共3例，血沉检测阴性合并CRP阳性患者共6例。 结论 同时使用血沉及CRP作为行翻修术患者的临床评价及检查指标，其临床漏诊率低，准确率高。 　　[关键词] 血沉；CRP；人工髋关节感染 　　[中图分类号] R722.12 [文献标识码] A [文章编号] 1674-0742（2016）04（a）-0058-02 　　[Abstract] Objective To evaluate and analyze the clinical application value of two indexes such as erythrocyte sedimentation rate and CRP in diagnosis and screening of hip arthroplasty infection and provide basis for the clinical promotion and application. Methods The clinical symptoms， signs and diseases histories of patients treated from November 2013 to March 2015 were retrospectively analyzed， and the erythrocyte sedimentation rate test results， CRP levels， intraoperative tissue cultivation， x-ray film， joint fluid？stab cultivation and case test results of patients were comprehensively analyzed. Results In the 146 cases of patients with artifical hip joint revision ， the hip arthroplasty infection was in 19 cases， among them， the ESR test was positive in 11 cases and negative in 8 cases， CRP was positive in 13 cases and negative in 6 cases， the positive ESR test combined with negative CRP was in 3 cases， the negative ESR test combined with positive CRP was in 6 cases， in the 127 cases with aseptic loosening， the ESR test was positive in 18 cases and negative in 109 cases， CRP was positive in 14 cases and negative in 113 cases， the specificity and sensitivity of CRP for patients with hip arthroplasty infection were respectively [88.90 ± 1.96 （0.029） %] and [69.15 ± 1.96 （0.108）%]， the clinical diagnosis accuracy rate was [19.02 ± 1.96 （0.028） %]， the specificity and sensitivity of ESR indexes for hip arthroplasty infection were respectively [84.26 ± 1.96 （0.029） %] and [56.88 ± 1.96 （0.109） %]， the clinical diagnosis accuracy rate was [19.98 ± 1.96 （0.031） %]. Conclusion The simultaneous use of ESR and CRP