甘精胰岛素阿卡波糖治疗老年糖尿病患者临床效果及预后分析.docVIP

甘精胰岛素阿卡波糖治疗老年糖尿病患者临床效果及预后分析 　　[摘要] 目的 研究甘精胰岛素+阿卡波糖治疗老年糖尿病患者的临床疗效及预后效果。方法 选取2014年6月―2017年6月该院收治的48例老年糖尿病患者作为研究对象，按照数字随机法将患者分成两组，一组采用甘精胰岛素进行治疗，为常规组，另一组则采用甘精胰岛素+阿卡波糖进行治疗，为研究组，对比分析两组患者的治疗效果和预后效果。结果 研究组患者治疗后与随访临床指标对比差异无统计学意义（P0.05），各项数据与常规组对比差异有统计学意义（P0.05）；常规组患者治疗后与随访数据中2 hPG、HbAlc、FCP 3项数据对比差异有统计学意义（P0.05）；常规组不良反应发生了为25%（6例），高于研究组的4.17%（1例）（P0.05）。结果 甘精胰岛素+阿卡波糖治疗老年糖尿病患者疗效明显，可有效改善患者各项临床指标，且维持时间长，预后效果佳，安全性也远优于单独使用甘精胰岛素，该用药方式在老年糖尿病患者的治疗中具有较高的使用价值。 　　[关键词] 甘精胰岛素；阿卡波糖；糖尿病；老年患者 　　[中图分类号] R587.1 [文献标识码] A [文章编号] 1672-4062（2017）11（b）-0056-02 　　[Abstract] Objective To research the clinical effect and prognosis of insulin glargine combined with acarbose in treatment of senile diabetes patients. Methods 48 cases of senile diabetes patients admitted and treated in our hospital from June 2014 to June 2017 were selected as the research objects and randomly divided into two groups， the routine group were treated with insulin glargine， while the research group were treated with insulin glargine combined with acarbose， and the treatment effect and prognosis effect were compared between the two groups. Results The differences in the clinical follow-up indicators after treatment between the two groups were not statistically significant（P0.05）， and the differences in various data between the two groups were statistically significant（P0.05）， and the differences in the 2 hPG， HbAlc， FCP between the two groups after treatment were statistically significant（P0.05）， and the incidence rate of adverse reactions in the routine group was higher than that in the research group（25% vs 4.17%， 6 cases vs 1 case）（P0.05）. Conclusion The curative effect of insulin glargine combined with acarbose in treatment of senile diabetes patients is obvious， which can effectively improve various clinical indicators， with long maintenance time， and good prognosis effect， and the safety is much better than that of single insulin glargin， which is of higher application value in treatment. 　　[Key words] Insulin g