神经内镜手术治疗颅底肿瘤应用研究.docVIP

神经内镜手术治疗颅底肿瘤应用研究 　　摘要：目的 分析神经内镜手术治疗颅底肿瘤的方式，探究其临床应用价值。方法 选择我院门诊在2014年5月～2016年5月期间所收治的60例颅底肿瘤患者作为研究对象，将其随机分为对照组和观察组各30例。对照组采取单纯显微镜手术方式，观察?M采取神经内镜手术方式，对两组患者的肿瘤切除率、并发症发生率和术后随访情况等进行对比分析。结果 观察组中有肿瘤全切除28例，次切除2例，并发症发生率为13.33%（4/30）；而对照组中有全切除21例，次切除7例和大部分切除2例，术后并发症发生率为36.67%（11/30），差异具有统计学意义（P0.05）。结论 神经内镜手术治疗颅底肿瘤，不仅能够提高手术的安全性，提高肿瘤切除率，而且还有效的缩短了手术时间，降低并发症的发生率，在临床中具有较高的推广应用价值。 　　关键词：神经内镜手术；颅底肿瘤；治疗应用 　　Application of Neuroendoscopic Surgery in the Treatment of Skull Base Tumors 　　LU Ping 　　（Department of Neurosurgery，General Hospital of Offshore Oil，Tianjin 300452，China） 　　Abstract：Objective To analyze the method of endoscopic sinus surgery for skull base tumors and explore its clinical value.Methods 60 patients with skull base tumors were selected from May 2014 to May 2016 in our hospital.The patients were randomly divided into control group and observation group（30 cases）.The control group was treated with simple microscope.The observation group was treated by neuroendoscopic surgery.The tumor resection rate，complication rate and postoperative follow-up were compared between the two groups.Results In the observation group，there were 28 cases of total resection and 2 cases of subtotal resection.The complication rate was 13.33%（4/30）.In the control group，there were 21 cases of total resection，7 cases of resection and 2 cases of resection，the incidence of postoperative complications was 36.67%（11/30），the difference was statistically significant（P0.05）.Conclusion Neuroendoscopic surgery for skull base tumors can improve the safety of the operation and improve the tumor resection rate，but also shorten the operation time and reduce the incidence of complications.It has high application value in clinical practice. 　　Key words：Neuroendoscopic surgery；Skull base tumors；Therapeutic applications 　　颅底肿瘤指的是发生在颅底及其相邻结构，可由颅内向颅外，或由颅外向颅内发展的一种肿瘤病症，在医学临床中较为常见的有垂体瘤、颅咽管瘤、鞍结节脑膜瘤以及海绵窦肿瘤等[1]。患有颅底肿瘤的患者主要表现为颅内压增高、视觉和嗅觉等功能减退、面部麻木或疼痛以及四肢无力等症状，对于患者的身体健康和生命安全构成了严重的威胁。目前，手术治疗是颅底肿瘤的主要方式，而神经内镜作为一种有效