米索前列醇在剖宫产加子宫肌瘤剔除术后应用.docVIP

米索前列醇在剖宫产加子宫肌瘤剔除术后应用 　　[摘要] 目的 观察在行剖宫产加子宫肌瘤剔除术患者术后预防性使用米索前列醇的效果。 方法 选取2015年1月～2016年12月在本院住院的足月妊娠合并子宫肌瘤，并行剖宫产术加子宫肌瘤剔除术的患者60例为治疗组，另取同时期在本院住院的足月妊娠并单纯行剖宫产术的患者60例为对照组。治疗组在术毕予米索前列醇400μg置直肠，对照组无给药，观察记录两组产妇在术毕至产后2h期间总出血量及出现产后宫缩乏力出血的情况。 结果 治疗组产妇在术毕至产后2h内的出血量少于对照组，产后宫缩乏力出血的发生率低于对照组，差异有统计学意义（P0.05）。 结论 术毕预防性给予米索前列醇直肠给药能有效地减少了患者产后2h内出血量及降低产后宫缩乏力出血发生率，适用于各级医院，尤其是基层医院，值得临床推广应用。 　　[关键词] 米索前列醇；直肠给药；产后2小时；宫缩乏力 　　[中图分类号] R737.33 [文献标识码] A [文章编号] 2095-0616（2017）14-83-03 　　Application of misoprostol in cesarean section plus myomectomy 　　ZHAO Shunzhi 　　Department of Obstetrics and Gynecology，Chenghai District People’s Hospital，Shantou 515800，China 　　[Abstract] Objective To observe the effect of prophylactic use of misoprostol after cesarean section plus myomectomy. Methods 60 cases of full-term pregnancy complicated with uterine myoma，concurrent cesarean section plus myomectomy hospitalized in our hospital from January 2015 to December 2016 were selected as the treatment group.Another 60 cases of term pregnancy and cesarean section at the same period in our hospital were selected as control group.Patients in treatment group wre treated with misoprostol 400ug rectum after operation.Patients in control group were with no drugs.The total amount of bleeding and the incidence of postpartum uterine atony bleeding in the two groups of mothers in the 2 hours after the completion of surgery were observed and recorded. Results The amount of bleeding in the treatment group was less than that in the control group within 2 hours after operation，the incidence of postpartum uterine atony hemorrhage was lower than that of the control group，the difference was statistically significant （P0.05）. Conclusion Prophylactic administration of misoprostol for rectal administration can effectively reduce the amount of bleeding within 2 hours after delivery and reduce the incidence of postpartum hemorrhage.It is suitable for all levels of hospitals，especially the primary hospital. It is worthy of clinical