纳洛酮联合尿激酶治疗急性心肌梗死临床效果分析.docVIP

纳洛酮联合尿激酶治疗急性心肌梗死临床效果分析 　　[摘要] 目的 探讨纳洛酮联合尿激酶对于治疗急性心肌梗死（AMI）的临床效果。方法 将该院76例AMI患者，均分成两组，各38例，两组在均行常规治疗的基础上，对照组给予尿激酶治疗，治疗组给予纳洛酮与尿激酶联合治疗。统计两组在不同时间段的心电图，并对比治疗前后两组的疗效。 结果 对照组的总有效率为65.8%，而治疗组的总有效率为92.1%，治疗组的疗效优于对照组，差异有统计学意义（P0.05）。从症状体征的对比上，治疗组的各指标恢复情况也优于对照组，差异有统计学意义（P0.05）。结论 相较于单纯使用尿激酶而言，纳洛酮联合尿激酶对于治疗AMI的有效性更高，更有助于缓解症状，值得临床推广。 　　[关键词] 急性心肌梗死；纳洛酮；尿激酶 　　[中图分类号] R743.33 [文献标识码] A [文章编号] 1674-0742（2015）05（a）-0134-02 　　Naloxone Joint Effect of Urokinase in the Treatment of Acute Myocardial Infarction 　　QI Da-Lei 　　Heart with greater hinggan mountains area in heilongjiang province peoples hospital， Heilongjiang 165000 China 　　[Abstract] Objective Discussion naloxone combined with urokinase for acute myocardial infarction （AMI） clinical results.Methods Our hospital76 cases of AMI patients were divided into two groups， each of 38 cases， the basis of both groups underwent conventional treatment， the control group was given urokinase therapy， the treatment group received naloxone combination therapy with urokinase. Statistical two different time periods in the electrocardiogram， and compare the efficacy of the two groups before and after treatment.Results The total effective rate of the control group 65.8%， while the total effective treatment group was 92.1% in the treatment group than the control group， the difference was significant， there is （P0.05）， the difference was statistically significant. From the comparison of symptoms and signs， and each treatment group recovery indicators are better than the control group， the differences are significant， there is （P0.05）5， the difference was statistically significant.Conclusion Compared to the simple use of urokinase， the naloxone combined with urokinase for higher effectiveness of the treatment of AMI， but also help relieve symptoms， worthy of promotion. 　　[Key words] Acute myocardial infarction； Naloxone； Urokinase 　　急性心肌梗死（acute myocardial infarction，AMI）是临床上常见的危重病，是导致猝死的主要原因，发病1 h内死亡率高达50%，心律失常、心力衰竭、心源性休克是重要的致死原因[1]。临床上有剧