脉氧监护仪在先天性心脏病筛查中应用.docVIP

脉氧监护仪在先天性心脏病筛查中应用 　　摘 要 目的：观察脉氧监护仪（Masimo Signal Extraction Technology， Masimo SET）在先天性心脏病筛查中的灵敏度及准确性。方法：选择2011年1月-2013年7月生后24 h内入住新生儿病房的256名新生儿为筛查对象，排除存在家族性遗传病、传染病、窒息、脐带异常、胎盘异常、严重贫血者。于生后48～72 h之间通过Masimo SET检测血氧饱和度，并对所有新生儿行心超检查确认。结果：256例新生儿中筛查阳性18例，阴性238例。经心超确认阳性病例中16例、阴性病例中10例为先天性心脏病，经统计学处理差异有显著性（P0.05）。Masimo SET检测先天性心脏病的敏感性为88.89%，特异性为95.79%。结论：Masimo SET对新生儿早期筛查先天性心脏病有较大的帮助。 　　关键词 新生儿 先天性心脏病 Masimo SET 筛查 　　中图分类号：R443.8； R541.1 文献标识码：B 文章编号：1006-1533（2014）19-0041-03 　　The value of Masimo SET in the diagnosis of congenital heart disease 　　WAN Jun， BAO Zhidan， LING Li， NIU Limei 　　（ Department of Neonatology， Jiangyin Hospital Affiliated to Medical School of Southeast University， Jiangyin 214400， China） 　　ABSTRACT Objective： To evaluate the sensitivity and accuracy of the pulse oxygen monitor （Masimo SET） in the screening of congenital heart disease. Methods： Two hundred and fifty-six babies born in 24 hours during January 2011 to July 2013 in our department were chosen for screening， excluding the presence of familial hereditary diseases， infectious diseases， asphyxia， abnormality of umbilical cord， placenta and severe anemia. Oxygen saturation in blood was assayed with Masimo SET within 48～72 hours after birth and echocardiography was performed to all the babies. Results： There were 18 positive cases and 238 negative cases in 256 neonates based on the screening of Masimo SET and later 16 cases of congenital heart diseases were confirmed by echocardiography in positive group and 10 cases in negative group. The differences were statistically significant （P0.05）. The sensitivity for Masimo SET to screen congenital heart disease was 88.89% with the specificity 95.79%. Conclusion： Masimo SET is of benefit to screening congenital heart disease in early stage of neonates. 　　KEY WORDS newborns； congenital heart disease； Masimo SET； screening 　　先天性心脏病是新生儿最常见的先天缺陷，在活产婴儿中约占0.9%。其中约有1/4的先天性心脏病患儿病情较严重，需要在生后1年内给予手术或介入治疗。重症的先天性心脏病（critical congenital heart disease，