补脾肾活血解毒法治疗慢性肾衰竭4～5期患者临床研究.docVIP

补脾肾活血解毒法治疗慢性肾衰竭4～5期患者临床研究 　　【摘要】 目的：研究补脾肾活血解毒法治疗慢性肾衰竭4～5期患者的临床疗效。方法：选取本院2015年6月-2016年2月80例慢性肾衰竭4～5期患者，分为对照组与观察组，每组各40例。对照组患者进行西医常规治疗和排毒治疗，观察组患者在西医常规治疗基础上联合补脾肾活血解毒法，比较两组患者的肾功能指标及临床疗效。结果：观察组患者治疗的总有效率为82.5%，明显高于对照组的52.5%，两组比较差异有统计学意义（P0.05）。治疗后，观察组患者的Scr、BUN、Ccr、Alb、Hb指标均明显优于对照组（P0.05）。结论：补脾肾活血解毒法治疗慢性肾衰竭4～5期患者疗效确切，安全性好，有利于延缓病情进展，提高患者的生活质量。 　　【关键词】 补脾肾活血解毒法； 慢性肾衰竭； 临床研究 　　【Abstract】 Objective：To study the clinical efficacy of Spleen and Kidney Huoxue Jiedu Decoction in the treatment of chronic renal failure patients with stage 4-5.Method：From June 2015 to February 2016，80 patients with chronic renal failure stage 4-5 were selected and divided into two groups，40 cases in each group.The control group was treated with routine treatment and detoxification，the observation group was treated on the routine treatment of western medicine combined with Spleen and Kidney Huoxue Jiedu Decoction method.The renal function indexes and clinical efficacy of two groups were compared.Result：The total effective rate was 82.5% in the observation group， which was significantly higher than that in the control group 52.5%（P0.05）.After treatment，Scr，BUN，Ccr，Alb and Hb in the observation group were significantly better than those in the control group（P0.05）.Conclusion：The treatment of Spleen and Kidney Huoxue Jiedu Decoction in patients with chronic renal failure stage 4-5 of effective and safe，it is conducive to delay the progress of the disease，improve the quality of life of patients. 　　【Key words】 Spleen and Kidney Blood Circulation； Chronic renal failure； Clinical study 　　First-author’s address：Jingdezhen Traditional Chinese Medicine Hospital，Jingdezhen 333000，China 　　doi：10.3969/j.issn.1674-4985.2017.31.037 　　?t学研究指出，慢性肾脏病患者面临的最大问题是残肾功能逐渐丢失，毒素及代谢产物逐步蓄积[1]。因此，患者最终需要进行肾脏替代治疗，西医疗法主要包括常规疗法（从饮食、延缓进展）和排毒治疗疗法[2]。近年来，临床研究发现，在西医常规疗法的基础上运用中药方剂，有利于缓解病情，提高患者生活质量[3]。基于此，本文拟以80例慢性肾衰竭4～5期患者为研究对象，研究补脾肾活血解毒法治疗慢性肾衰竭4～5期患者的临床疗效，现报道如下。 　　1 资料与方法 　　1.1 一般资料 本研究自2015年6月-2016年2月，以单盲法纳入80例慢性肾衰竭4～5期患者，全部患