针刺足三里悬钟对缺血性中风患者脑功能磁共振成像影响研究.docVIP

针刺足三里悬钟对缺血性中风患者脑功能磁共振成像影响研究 　　[摘要] 目的 探讨应用fMRI技术分析针刺缺血性中风患者足三里、悬钟对脑fMRI的影响。 方法 选择我院2012年1月～2014年12月收治的60例缺血性脑中风患者随机分为对照组和治疗组，每组30例，对照组采用缺血性中风基本治疗；治疗组在对照组治疗的基础上加针灸足三里、悬钟。两组患者在治疗的第1、10、20天接受fMRI扫描，采用静息-刺激交替模式，所得数据经SPM2分析。 结果 治疗组激活区主要为双侧颞中回、额中回、额上回，同侧岛叶、枕上回以及对侧中央前回、中央后回、岛盖、角回等。治疗组第20天fMRI图像上激活区的数目较第1天明显增加，差异有统计学意义（P0.05）。治疗组在治疗第20天fMRI图像上激活区数目和范围与对照组相比，差异有统计学意义（P0.01）。 结论 针刺足三里、悬钟能促进缺血性脑中风患者康复，fMRI技术直观性证明该疗法的有效性，为祖国中医针灸学方面的研究提供了一种可信赖的方法。 　　[关键词] 脑缺血；针灸疗法；足三里穴；悬钟穴；磁共振 　　[中图分类号] R246.6 [文献标识码] B [文章编号] 1673-9701（2015）30-0071-03 　　Study on the impact of acupuncture of Zusanli and Xuanzhong in brain functional magnetic resonance imaging of patients with ischemic stroke 　　LI Qing1 ZHOU Dingzhong1 XIE Juying2 YAN Jianhui3 LI Tao1 　　1.Department of Radiology，Affiliated Hospital of Xiangnan University in Hunan Province，Chenzhou 423000，China；2.Department of Rehabilitation，Affiliated Hospital of Xiangnan University in Hunan Province，Chenzhou 423000，China；3.Department of Neurology，Affiliated Hospital of Xiangnan University in Hunan Province，Chenzhou 423000，China 　　[Abstract] Objective To investigate the impact of acupuncture of Zusanli and Xuanzhong in brain functional magnetic resonance imaging of patients with ischemic stroke. Methods A total of 60 cases of ischemic stroke patients admitted in our hospital from January 2012 to December 2014 were randomly divided into the control group and the treatment group， with 30 patients in each group. The control group received the basic treatment of ischemic stroke，and the treatment group received acupuncture Zusanli and Xuanzhong on the basis of the control group. Two groups of patients in the first，10th and 20th day of the treatment，accepted fMRI scans in resting-stimulate alternating pattern，and the obtained data was analyzed by SPM2. Results The active region of the treatment group were mainly bilateral temporal gyrus，middle frontal gyrus，superior frontal gyrus，insula ipsilateral，pillow back and contralateral medial frontal g