高血压与颈动脉粥样硬化关系探究.docVIP

高血压与颈动脉粥样硬化关系探究 　　DOI：10.16662/j.cnki.1674-0742.2017.07.044 　　[摘要] 目的 分析高血?憾跃倍?脉粥样硬化的影响，为高血压患者脑血管病一级预防提供依据。方法 2013年2月―2015年11月，医院神经内科收治的高血压伴颈动脉粥样硬化患者75例，病程10年患者纳入长病程组，进行颈动脉超声、MRI检查，对比检查结果。结果 短病程组L-IMT、R-IMT、狭窄处最小管径、狭窄斑块累及长度分别为（0.76±0.13）、（0.77±0.11）、（3.8±1.10）、（5.3±4.30）mm，中病程组分别为（0.78±0.13）、（0.78±0.12）、（3.5±1.00）、（17.4±5.60）mm，长病程组分别为（0.93±0.20）、（0.88±0.16）、（2.7±0.60）、（28.3±4.30）mm，差异有统计学意义（P0.05）；长病程者重度狭窄率、活动性斑块检出率、内膜增厚率分别为40.00%、24.00%、44.00%高于短病程组4.00%、0.00%、8.00%，差异有统计学意义（P0.05）。结论 高血压与颈动脉粥样硬化关系密切，随着病程的延长，患者颈动脉硬化病情越严重。 　　[关键词] 颈动脉粥样硬化；高血压；发病机制 　　[中图分类号] R54 [文献标识码] A [文章编号] 1674-0742（2017）03（a）-0044-03 　　Study on Correlation between Hypertension and Carotid Artherosclerosis 　　SHI Li-bo 　　Department of Neurology， Honghe First People’s Hospital， Honghe， Yunnan Province， 661100 China 　　[Abstract] Objective To analyze the effect of hypertension on the carotid artherosclerosis and provide basis for the first-class prevention of cerebrovascular disease of patients with hypertension. Methods 75 cases of patients with hypertension and carotid artherosclerosis admitted and treated in the department of neurology in our hospital from February 2013 to November 2015 were selected and divided into three groups， 25 cases whose disease course 10 years were selected as the long disease course group， and the patients were given the carotid artery ultrasound and MRI examinations， and the examination results were compared. Results The differences in the L-IMT， R-IMT， min pipe diameter of stricture and narrow plaque involved length between the short， middle and long disease course groups had statistical significance， [（0.76±0.13），（0.77±0.11），（3.8±1.10），（5.3±4.30）mm vs （0.78±0.13），（0.78±0.12），（3.5±1.00），（17.4±5.60）mm vs （0.93±0.20），（0.88±0.16），（2.7±0.60），（28.3±4.30）mm]（P0.05）， and the severe stenosis rate， active plaque detection rate and intima thickening rate in the long disease course group were higher than those in the short disease course group， （40.00%，24.00%，44.00% v