高龄糖尿病合并慢性肾脏病患者行前列地尔治疗安全性分析.docVIP

高龄糖尿病合并慢性肾脏病患者行前列地尔治疗安全性分析 　　DOI：10.16658/j.cnki.1672-4062.2016.08.023 　　[摘要] 目的 探析高龄糖尿病合并慢性肾脏病患者行前列地尔治疗的安全性。方法 回顾性分析2015年1月―2016年1月该院收治的92例高龄糖尿病合并慢性肾脏病患者的临床资料，按治疗方案不同分为对照组（40例）和研究组（52例），对照组行常规治疗，研究组在其基础上行前列地尔治疗，对比两组治疗效果以及不良反应。结果 治疗后研究组空腹血糖、血尿素氮、24 h尿蛋白定量以及血肌酐均显著优于对照组，比较差异有统计学意义（P0.05）。结论 高龄糖尿病合并慢性肾脏病患者行前列地尔治疗效果显著，且安全性高，值得推广。 　　[关键词] 糖尿病；慢性肾脏病；高龄患者；前列地尔；安全性 　　[中图分类号] R587.2 [文献标识码] A [文章编号] 1672-4062（2016）04（b）-0023-02 　　Safety Analysis for Patients with Chronic Kidney Disease Alprostadil in Treatment of Senile Diabetes 　　DUAN De-Fang1，WANG Ming2 　　1.The second Internal Medicine ，the peoples Hospital of Feicheng city，Taian， Shandong Province，271600 China；2.The Department of orthopedics of Feicheng Hospital of Traditional Chinese Medicine，Taian，Shandong Province，271600 China 　　[Abstract] Objective To investigate elderly diabetic patients with chronic kidney disease were treated with alprostadil safety of the treatment. Methods A retrospective analysis of January 2015 - January 2016 in our hospital 92 cases of elderly diabetic patients with chronic kidney disease clinical data， according to the different treatment options，the patients were divided into control group （40 cases） and study group （52 cases） the control group underwent conventional treatment， treatment in the study group based its upstream alprostadil， compared two groups of therapeutic effects and adverse reactions. Results After treatment， the study group fasting blood glucose， blood urea nitrogen， 24h urine protein and serum creatinine were significantly better than the control group， the difference was statistically significant（P0.05）. Conclusion The elderly diabetic patients with chronic kidney disease row alprostadil treatment effect is remarkable， and safe， and it is worthy to be popularized. 　　[Key words] Diabetes； Chronic kidney disease； Elderly patients； Alprostadil； Security 　　糖尿病合并慢性肾脏病为临床较为常见疾病，好发于老年人群，致死率较高，且近年来，随着我国社会老龄化的不断加重，该病发病率不断呈上升趋势，严重危害患者生命安全，因此，对患者予以有效治疗具重要意义[1]。为探究较好治疗方案，