高龄老人黄斑区视网膜厚度测量研究.docVIP

高龄老人黄斑区视网膜厚度测量研究 　　【摘要】 目的 研究高?g老人黄斑区视网膜厚度的分布情况。方法 采用频域光学相干断层扫描（SD-OCT）对62例（62只眼）80～90岁健康老人黄斑区视网膜进行扫描， 依据系统默认的ETDRS分区， 测量9个分区内厚度及内环（即0～3 mm直径区域）总厚度， 测量区（即0～6 mm直径区域）总厚度， 黄斑中心凹厚度。采用独立样本t检验比较性别、眼别之间的厚度差异；采用直线相关系数分析年龄与黄斑中心凹、黄斑中心区、内环总厚度、测量区总厚度之间的相关关系。结果 右眼与左眼， 男性右眼与左眼黄斑中心凹及各区域平均厚度比较差异无统计学意义（P0.05）。男性与女性， 女性右眼与左眼， 男性与女性右眼黄斑中心凹及各区域平均厚度比较， 除中心区差异有统计学意义（P0.05）。男性与女性左眼黄斑中心凹及各区域平均厚度比较， 除内环下方区域差异有统计学意义（P0.05）。年龄与黄斑中心凹、黄斑中心区、内环总厚度、测量区总厚度之间无相关关系（P0.05）。结论 测量并研究高龄老人黄斑区视网膜厚度值的特点， 可以为临床诊治该年龄段人群的黄斑疾病提供数值参考。 　　【关键词】 黄斑；视网膜；光学相干断层扫描；高龄老人；正常参考值 　　DOI：10.14163/j.cnki.11-5547/r.2016.32.015 　　【Abstract】 Objective To research distribution of retinal thickness in macular region of senile people. Methods Spectral-domain optical coherence tomography （SD-OCT） was applied to scan retina in macular region in 62 healthy senile people （62 eyes） aging 80～90 years old. Measurement was made in accordance with default ETDRS partition on 9 parts thickness， total thickness of inner ring （diameter within 0～3 mm）， total thickness of measurement zone （diameter within 0～6 mm） and central fovea of macula thickness. Independent sample t test was applied to compare difference of thickness between gender and eyes. Linear correlation coefficient was applied to analyze correlation between age， central fovea of macula， central macula， total thickness of inner ring， and total thickness of measurement zone. Results There was no statistically significant difference of central fovea of macula and mean area thickness between right eye and left eye in male （P0.05）. Comparison of central fovea of macula and mean area thickness between right eye and left eye in female， and between right eye in male and female showed statistically significant difference of central area （P0.05）. The difference of thickness under inner ring had statistical significance between left eye in male and female （P0.05）. There was no correlation between age and central fovea of macula， central macula， total thickness of inner ring， and total th