某高校幼儿园附小儿童麻疹与脊髓灰质炎抗体水平检测分析.docVIP

某高校幼儿园附小儿童麻疹与脊髓灰质炎抗体水平检测分析 　　doi：10.3969/j.issn.1007-614x.2014.14.68 　　摘 要 目的：为了解某高校幼儿园、附小儿童麻疹、脊髓灰质炎（脊灰）抗体水平，评价免疫效果，制定科学的免疫预防策略，实现消除麻疹和维持无脊灰状态提供参考依据。方法：采取某高校幼儿园、附小2～12岁儿童的手指末梢血，采用酶联免疫吸附试验（ELISA）法检测麻疹、脊灰IgG抗体水平。结果：共检测样本2 191例，麻疹IgG抗体阳性2 130份，阳性率97.22%；脊灰抗体阳性2 168份，阳性率98.95%。不同性别、不同年龄组儿童麻疹和脊灰抗体阳性率差异均无统计学意义。结论：该校免疫规划工作成效显著，对适龄儿童进行麻疹、脊灰疫苗常规免疫加强化免疫及查漏补种能使儿童获得较高的免疫保护屏障，应持续认真开展。 　　关键词 儿童 麻疹 脊灰抗体 　　Detection and analysis of a university affiliated kindergarten，primary school children measles and polio antibody levels 　　Yang Peijuan，Li Qiong 　　The hospital of China West Normal University，637002 　　Abstract Objective：To understand the measles and poliomyelitis（polio）antibody level of a university affiliated kindergarten and primary school children，and evaluate the immune effects.Then making scientific immune prevention strategies，to achieve the elimination of measles and to provide reference for maintenance without poliomyelitis.Methods：Take peripheral finger blood of the kindergarten and primary school affiliated to China West Normal University 2～12 years old children，by using enzyme linked immunosorbent assay（ELISA）method for detection of measles and poliomyelitis antibody level of IgG.Results：A total of 2191 copies of test sample，the measles IgG antibody was positive in 2130 copies，and the positive rate was 97.22%.Poliomyelitis antibody positive 2168，and positive rate 98.95%.Differences in different age groups of children measles and polio antibody positive rate in different gender were no significant.Conclusion：Immune planning of the school is effective.Measles，polio vaccine in routine immunization and strengthening immunity and timely vaccination can make children get the immune protective barrier higher for school-age children，so it should continue to carry out. 　　Key words Children；Measles；Poliomyelitis antibody 　　麻疹、脊灰均是严重危害儿童健康的急性传染病，是WHO扩大免疫规划重点控制的疾病。某高校幼儿园、附小儿童在常规免疫的基础上，历年来曾多次开展麻疹疫苗、脊灰疫苗的查漏补种和强化免疫工作。为了解该校儿童麻疹、脊灰抗体水平，评价免疫效果，制定科学的免疫预防策略，实现消除麻疹和维持无脊灰状态。2012年3