创伤弧菌聚集缺失突变株库之构筑-嘉南药理大学图书馆.PDF

理 CNBT94-09 行94 年1 1 94 年12 31 95 年02 28 Vibrio vulnificus率 2-3 臨 刺 爛 力 率年來例 療 更不 來 antimicrobial peptides complement defensin polymyxin B…. 殺 (polymyxin B)行 polymyxin B 更 殺 來 殺 利 利行率 殺 ( Vibrio vulnificus) 率 年來例 (Bisharat et al., 1999; Hlady and Klontz, 1996; Paik et al., 1995) 臨 狀1.(primary septicemia) 類臨 狀 率 50%(Blake et al., 1979; Klontz et al., 1988; Chuang et al., 1992; Shapiro et al., 1998) (Klontz et al., 1988; Chuang et al., 1992) 2 (Blake et al., 1979; Klontz et al., 1988; Chuang et al., 1992) 2.(wound infection) 理 刺爛 若惡 率25% (Blake et al., 1979; Klontz et al., 1988; Chuang et al., 1992; Shapiro et al., 1998) 3. 狀 痢 復異 都 易 (Tacket et al., 1984) 來 1996 2002例 了 126% (Centers for Disease Control and Prevention) 臨 例 年 不 (Chuang et al., 1992; Chang et al., 1994; Hsueh et al., 2004) 了(Yoshida etal., 1985) 離(TrkA; Chen et al., 2004) 力 (lipase) (phospholipase) (DNase) (protease) (hemolysin) (cytolysin) (Kreger and Lockwood, 1981; Olive et al., 1986) type IV leader peptidase/N-methyltransferase (Paranjpye et al., 1998) 行 率(LD50) 不 (Shao and Hor, 2000; Wright and Morris, 1991) 殺 都 殺殺 (capsule) 殺 殺 (cationic antimicrobial peptides) (complement)bactericidal/permeability-increas- ing protein (BPI) defensin (Levy, 2000) 殺 洞 (Hankcock et