上海张江社区中老年人胃食管反流病患病状况的研究.docVIP

上海张江社区中老年人胃食管反流病患病状况的研究 　　摘 要 目的：调查上海浦东张江社区中老年人胃食管反流病（GERD）的患病状况。方法：采用整群随机抽样方法抽取上海张江镇10个社区共2 007名中老年人，用RDQ和GERDQ量表调查中老年人中GERD的患病率，分析与食管外表现的关系。结果：RDQ量表筛选的GERD患病率为4.9%，GERDQ量表筛选的GERD患病率为7.8%。食管外表现中慢性咳嗽、复发性中耳炎、咽炎/咽喉部异物感、喉炎与GERD密切相关。结论：GERD在社区人群中患病率较高，且与食管外表现关系密切。 　　关键词 胃食管反流病；中老年人；RDQ量表；GERDQ量表 　　中图分类号：R571 文献标志码：A 文章编号：1006-1533（2018）12-0036-03 　　Study of the prevalence of gastroesophageal reflux disease in middle-aged and elderly people in Zhangjiang Community， Shanghai 　　WANG Bo1， HU Yedong2， LIU Fei2， CHEN Yongqun1（1. General Medicine Department of Zhangjiang Community Health Service Center， Shanghai 201210， China； 2. Department of Gastroenterology of East Hospital affiliated to Tongji University， Shanghai 200120， China） 　　ABSTRACT Objective： To investigate the prevalence of gastroesophageal reflux disease（GERD） in middle-aged and elderly people in Zhangjiang Community， Pudong New District， Shanghai. Methods： A total of 2 007 middle-aged and elderly people from 10 communities in Zhangjiang Town， Shanghai were selected with cluster random sampling method， and RDQ and GERDQ scales were used to investigate the prevalence of GERD in middle-aged and elderly people. The relationship with the external manifestations of the esophagus was analyzed. Results： The prevalence of GERD screened by RDQ scale was 4.9% and the prevalence of GERD by GERDQ scale was 7.8%. In extra-esophageal manifestations chronic cough， recurrent otitis media， pharyngitis/throat foreign body sensation and laryngitis were closely related to GERD. Conclusion： GERD has a high prevalence in the community population and is closely related to extra-esophageal manifestations. 　　KEY WORDS gastroesophageal reflux disease； middle-aged and elderly people； RDQ score； GERDQ score 　　胃食管反流病（Gastroesophageal Reflux Disease，GERD）可导致患者生活质量明显下降。欧美国家GERD的患病率为10%～20%[1]，东亚地区的患病率为5.2%～8.5%[2]。一项全球的系统回顾研究显示，随着经济发展、人口老龄化和人们生活方式的改变，GERD发病率有逐渐增高的趋势，尤其在中老年人中[3]。由于中老年人常伴有多个慢性疾病，如冠心病、慢性支气管炎等，而慢性咳嗽、非心源性胸痛等GERD食管外症状，常常与肺部